575469-44-2Relevant articles and documents
Novel amalgamation of 2-styrylchromones and 1,2,4-triazole: Synthesis, antimicrobial evaluation and docking study
Nikam, Mukesh Dattatray,Mahajan, Pravin Sudhakar,Damale, Manoj Gangadhar,Sangshetti, Jaiprakash Navnath,Chate, Asha Vasantrao,Dabhade, Sanjay Kisan,Gill, Charansingh Harnamsingh
, p. 650 - 660 (2015)
A novel series of 1,2,4-triazole clubbed (E)-5-(4-(1 H-1,2,4-triazol-1-yl)phenyl)-1-(2-hydroxyphenyl)pent-4-ene-1,3-dione (4a-h) and 2-(4-(1 H-1,2,4-triazol-1-yl)styryl)-4H-chromen-4-one (5a-h) derivatives have been synthesized by ultrasound and conventio
Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes
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, (2008/06/13)
Novel amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employing these compounds and compositions. The compounds show a high and selective binding affinity to the histamine H3 receptor indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity. As a result, the compounds are useful for the treatment of diseases and disorders related to the histamine H3 receptor.