577743-54-5

Basic information

• Product Name: Oxiranemethanamine, N-(phenylmethyl)-N-(3-phenyl-2-propynyl)-
• CAS NO: 577743-54-5
• Molecular Formula: C19H19NO
• Molecular Weight: 277.366
• Mol File: 577743-54-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Oxiranemethanamine, N-(phenylmethyl)-N-(3-phenyl-2-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanamine, N-(phenylmethyl)-N-(3-phenyl-2-propynyl)-(577743-54-5)
• EPA Substance Registry System: Oxiranemethanamine, N-(phenylmethyl)-N-(3-phenyl-2-propynyl)-(577743-54-5)

Safety Data

• Hazardous Substances Data: 577743-54-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 1197-51-9 N-propargylbenzylamine 
• 40032-57-3 N-(3-phenylprop-2-ynyl)benzenemethanamine 
• 106-89-8 epichlorohydrin 

Relevant articles and documents

Nickel-catalyzed reductive coupling of alkynes and epoxides

Nickel-catalyzed, intramolecular and intermolecular reductive coupling of alkynes and epoxides affords synthetically useful homoallylic alcohols of defined alkene geometry. Very high regioselectivity is generally observed, and cyclizations proceed with complete selectivity for endo epoxide opening. This catalytic reaction represents the first use of a non-π-based electrophile in a growing class of nickel-catalyzed, multicomponent coupling reactions, and is the first catalytic method of reductive coupling of alkynes and epoxides that is effective for both intermolecular and intramolecular cases, and mechanistically distinct from these, possibly involving a nickella(II)oxetane. Copyright