5782-69-4Relevant articles and documents
THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
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, (2013/02/28)
Provided are compounds with the following structure, formula (I) pharmaceutically acceptable salts thereof, use of those compounds for treating cancer and pharmaceutical compositions comprising those compounds.
ANTI-VIRAL COMPOUNDS
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Page/Page column 62, (2008/12/08)
Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
Synthesis and solid-state structures of alkyl-substituted 3-cyano-2-pyridones
Fischer, Christian B.,Polborn, Kurt,Steininger, Harald,Zipse, Hendrik
, p. 1121 - 1131 (2007/10/03)
A series of 3-cyano-pyridones carrying a variety of alkyl substituents at C-5 and C-6 has been synthesized and their solid-state structures have been studied. Hydrogen bonding interactions between individual pyridone molecules lead either to the formation of symmetric dimers of the R2 2(8) type or to helical chains of the C(4) type. Based on known and calculated structures for the 2-pyridone parent system, the solid-state structures can be divided in two groups representing cases with little external influence on the hydrogen bonding array (group A) and those with a larger external influence (group B).