57956-46-4

Basic information

• Product Name: methyl (4E)-2,2-dimethyl-5-phenyl-3-trimethylsilyloxypentanoate
• Synonyms: methyl (4E)-2,2-dimethyl-5-phenyl-3-trimethylsilyloxypentanoate
• CAS NO: 57956-46-4
• Molecular Weight: 308.493
• Mol File: 57956-46-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: methyl (4E)-2,2-dimethyl-5-phenyl-3-trimethylsilyloxypentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (4E)-2,2-dimethyl-5-phenyl-3-trimethylsilyloxypentanoate(57956-46-4)
• EPA Substance Registry System: methyl (4E)-2,2-dimethyl-5-phenyl-3-trimethylsilyloxypentanoate(57956-46-4)

Safety Data

• Hazardous Substances Data: 57956-46-4(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 31469-15-5 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene 
• 30076-98-3 (3,3-dimethoxypropyl)benzene 

Downstream Products

• 57956-40-8 methyl 3-hydroxy-2,2-dimethyl-5-phenylpentanoate 

Relevant articles and documents

Spontaneous aldol and Michael additions of simple enoxytrimethylsilanes in DMSO

Activation of simple trimethylsilyl ketene acetals by dipolar aprotic solvents has been evidenced, allowing efficient solvent assisted aldol and Michael additions under extremely simple, mild and metal free conditions. (C) 2000 Elsevier Science Ltd.

Mesoporous aluminosilicate-catalyzed Mukaiyama aldol reaction of aldehydes and acetals

A mesoporous aluminosilicate (Al-MCM-41) was found to be an effective heterogeneous catalyst for the reaction of both aldehydes and acetals with silyl enol ethers or ketene silyl acetals to give the corresponding aldol adducts in moderate to high yields. The remarkable high catalytic activity of Al-MCM-41 over amorphous silica-alumina and aluminum-free mesoporous silicate was observed in the reaction. The solid acid catalyst could be recovered easily by filtration and the recovered catalyst was reusable in the same reactions without a significant loss of catalytic activity.

Quaternary ammonium dendrimers as Lewis base catalysts for Mukaiyama-Aldol reaction

Surface-alkylated poly(propylene imine) dendrimer was treated with methyl iodide to afford quaternarized ammonium iodide dendrimer. The quaternarized dendrimer catalyzed the Mukaiyama-Aldol reaction of trimethylsilyl acetal with various aldehydes as a Lew