58088-57-6

Basic information

• Product Name: PHENYL-PYRIDIN-4-YLMETHYL-AMINE
• Synonyms: C-PHENYL-C-PYRIDIN-4-YL-METHYLAMINE DIHYDROCHLORIDE;PHENYL-PYRIDIN-4-YLMETHYL-AMINE;Phenyl(pyridin-4-yl)methanamine dihydrochloride;1-phenyl-1-(pyridin-4-yl)-methylamine;alpha-(4-Pyridyl)benzylamine;alpha-Phenyl-4-pyridinemethanamine;4-Pyridinemethanamine,alpha-phenyl
• CAS NO: 58088-57-6
• Molecular Formula: C₁₂H₁₂N₂
• Molecular Weight: 184.24
• EINECS: 214-767-6
• Mol File: 58088-57-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 104℃
• Boiling Point: 335℃
• Flash Point: 177℃
• Appearance: /
• Density: 1.106
• Vapor Pressure: 0.00012mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: PHENYL-PYRIDIN-4-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-PYRIDIN-4-YLMETHYL-AMINE(58088-57-6)
• EPA Substance Registry System: PHENYL-PYRIDIN-4-YLMETHYL-AMINE(58088-57-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 58088-57-6(Hazardous Substances Data)

Usage

General Description

Phenyl-pyridin-4-ylmethyl-amine is a chemical compound derived from the amine group. It comprises a phenyl ring structure attached to a pyridin-4-ylmethyl group through an amine linkage. This structure implies the potential presence of properties typical to aromatic compounds and amines. However, detailed information about its specific physical and chemical properties, uses, toxicity, and ecological effects is not readily available in public databases, indicating that this compound is not widely used or studied. Thus, it could be a substance primarily of interest in specific research or industrial contexts.

InChI:InChI=1/C12H12N2/c13-12(10-4-2-1-3-5-10)11-6-8-14-9-7-11/h1-9,12H,13H2/p+1/t12-/m1/s1

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 14548-46-0 4-Benzoylpyridine 
• 71-43-2 benzene 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 423761-51-7 N-(phenyl-pyridin-4-yl-methyl)-formamide 

Downstream Products

• 95899-12-0 C₁₅H₁₄N₄S 
• 229953-04-2 C₂₉H₂₂N₄O 
• 95899-17-5 C₁₇H₁₇N₅ 
• 95899-16-4 C₁₆H₁₇N₅ 
• 95899-15-3 C₁₅H₁₅N₅ 
• 1009370-66-4 rac-4-fluoro-N-{[(phenylpyridin-4-ylmethyl)carbamoyl]methyl}benzamide 

Relevant articles and documents

PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS

Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.

Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Synthesis of primary amines via nucleophilic addition of organometallic reagents to aldimines on solid support

Resin-immobilized aldimines 5, derived from the condensation of amine-functionalized Rink polystyrene resin with aldehydes, react with Grignard reagents, lithium reagents or LiBH4 to afford a wide variety of primary amines in good to excellent yields upon trifluoroacetic acid cleavage. In this amine synthesis, Rink resin functions both as a solid support and as a NH protecting group.