58089-32-0

Basic information

• Product Name: (1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID
• Synonyms: (BENZOOXAZOL-2-YLSULFANYL)-ACETIC ACID;ASISCHEM C58435;LABOTEST-BB LT00065346;(1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID;AKOS BC-1522;AKOS BBS-00001869;ZERENEX E/6020004;2-(1,3-benzoxazol-2-ylsulfanyl)ethanoic acid
• CAS NO: 58089-32-0
• Molecular Formula: C₉H₇NO₃S
• Molecular Weight: 209.22
• Mol File: 58089-32-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 399.4 °C at 760 mmHg
• Flash Point: 195.3 °C
• Appearance: /
• Density: 1.48 g/cm³
• Vapor Pressure: 4.28E-07mmHg at 25°C
• CAS DataBase Reference: (1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID(58089-32-0)
• EPA Substance Registry System: (1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID(58089-32-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 58089-32-0(Hazardous Substances Data)

Usage

General Description

(1,3-Benzoxazol-2-ylthio)acetic acid is a chemical compound with the molecular formula C10H7NO3S. It is a benzoxazole derivative with a thioacetic acid group attached to the benzoxazole ring. (1,3-BENZOXAZOL-2-YLTHIO)ACETIC ACID is used in pharmaceutical research and development as a potential drug candidate due to its unique structure and potential pharmacological properties. Additionally, it is used as a reagent in organic synthesis for the preparation of various heterocyclic compounds. The compound's chemical structure and properties make it a valuable tool in the field of medicinal and synthetic chemistry.

InChI:InChI=1/C9H7NO3S/c11-8(12)5-14-9-10-6-3-1-2-4-7(6)13-9/h1-4H,5H2,(H,11,12)/p-1

Upstream product

• 79-11-8 chloroacetic acid 
• 2382-96-9 2-sulfanyl-1,3-benzoxazole 
• 95-55-6 2-amino-phenol 
• 15091-70-0 2-mercaptobenzoxazole sodium salt 
• 73824-25-6 benzoxazol-2'-yl-mercaptoacetic acid ethyl ester 
• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 3926-62-3 sodium monochloroacetic acid 

Downstream Products

• 79420-03-4 2-(Benzooxazol-2-ylsulfanyl)-N-[4-(4-methoxy-phenyl)-thiazol-2-yl]-acetamide 
• 86109-51-5 2-(benzo[d]oxazol-2-ylthio)-N-(naphthalen-1-yl)acetamide 
• 86109-47-9 2-(Benzooxazol-2-ylsulfanyl)-N-(4-methoxy-phenyl)-acetamide 
• 86109-43-5 2-(benzo[d]oxazol-2-ylthio)-N-phenylacetamide 
• 311777-95-4 2-(Benzooxazol-2-ylsulfanyl)-N-benzyl-acetamide 
• 86109-44-6 2-(Benzooxazol-2-ylsulfanyl)-N-(4-bromo-phenyl)-acetamide 
• 28178-42-9 2,6-diisopropylphenyl isocyanate 
• 2958-62-5 mesityl isocyanate 
• 16105-44-5 benzooxazol-2-yl-acetic acid ethyl ester 

Relevant articles and documents

Synthesis and neurotropic properties of 2-(carboxymethylthio) derivatives of benzimidazole, benzothiazole and their ammonium salts

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Synthesis of Benzoxazolylthiomethyl and Benzthiazolylthiomethyl Quinazolin-4(3 h)-ones

o-Aminophenol (1a, X = O) or o-aminothiophenol (1b, X = S) was reacted with carbon disulfide in ethanol containing KOH under reflux to obtain 2-mercaptobenzoxazole (2a, X = O) and 2-mercaptobenzthiazole (2b, X = S), respectively. Condensation of 2a and 2b each with chloroacetic acid gave 2-(benzoxazol-2-ylthio)acetic acid (3a, X = O) and 2-(benzthiazol-2-ylthio)acetic acid (3b, X = S) respectively which with anthranilamide gave 2-((benzoxal-2-ylthio)methyl) quinazolin-4(3H)-one (5a, X = O) and 2-((benzthiazol-2-ylthio)methyl)quinazolin-4(3H)-one (5b, X = S) respectively. The products 5a,b could be prepared in three other routes involving the general sequences 6→2→5, 6→7→5 and 8→9→5.

Some azolythioacetamides and their analgesic and antiinflammatory activities

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