58138-59-3

Basic information

• Product Name: 2-acetoxy-5-methylbenzoyl chloride
• Synonyms: 2-acetoxy-5-methylbenzoyl chloride
• CAS NO: 58138-59-3
• Molecular Weight: 212.633
• Mol File: 58138-59-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-acetoxy-5-methylbenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetoxy-5-methylbenzoyl chloride(58138-59-3)
• EPA Substance Registry System: 2-acetoxy-5-methylbenzoyl chloride(58138-59-3)

Safety Data

• Hazardous Substances Data: 58138-59-3(Hazardous Substances Data)

Upstream product

• 89-56-5 5-Methylsalicylic acid 
• 14504-08-6 2-acetoxy-5-methylbenzoic acid 

Downstream Products

• 1237520-18-1 C₃₆H₄₅N₃O₇ 
• 1237515-89-7 2-(5-(((2-(dimethylamino)ethyl)(methyl)amino)methyl)-2-hydroxybenzamido)-4-phenylbenzoic acid 
• 1237520-19-2 tert-butyl 2-(5-(((2-(dimethylamino)ethyl)(methyl)amino)methyl)-2-(methoxymethoxy)benzamido)-4-phenylbenzoate 
• 1237520-16-9 tert-butyl 2-(2-(methoxymethoxy)-5-((piperidin-1-yl)methyl)benzamido)-4-phenylbenzoate 
• 1237520-14-7 tert-butyl 2-(2-(methoxymethoxy)-5-((4-propylpiperazin-1-yl)methyl)benzamido)-4-phenylbenzoate 
• 1237520-11-4 tert-butyl 2-(2-(methoxymethoxy)-5-((4-methylpiperazin-1-yl)methyl)benzamido)-4-phenylbenzoate 
• 1237515-65-9 tert-butyl 2-(5-(bromomethyl)-2-(methoxymethoxy)benzamido)-4-phenylbenzoate 
• 1237520-10-3 tert-butyl 2-(2-(methoxymethoxy)-5-methylbenzamido)-4-phenylbenzoate 
• 1237515-64-8 tert-butyl 2-(2-hydroxy-5-methylbenzamido)-4-phenylbenzoate 
• 1010121-91-1 (2-hydroxy-5-methylbenzoyl)-N-(5-chlorothiazol-2-yl)amine 

Relevant articles and documents

Synthesis and antioxidant activities of berberine 9-: O -benzoic acid derivatives

Although berberine (BBR) shows antioxidant activity, its activity is limited. We synthesized 9-O-benzoic acid berberine derivatives, and their antioxidant activities were screened via ABTS, DPPH, HOSC and FRAP assays. The para-position was modified with halogen elements on the benzoic acid ring, which led to an enhanced antioxidant activity and the substituent on the ortho-position was found to be better than the meta-position. Compounds 8p, 8c, 8d, 8i, 8j, 8l, and especially 8p showed significantly higher antioxidant activities, which could be attributed to the electronic donating groups. All the berberine derivatives possessed proper lipophilicities. In conclusion, compound 8p is a promising antioxidant candidate with remarkable elevated antioxidant activity and moderate lipophilicity.

N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An N-acyl anthranilic acid derivative represented by general formula (1) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl group or th

Novel quinolizidine salicylamide influenza fusion inhibitors

A novel series of quinolizidine salicylamides was synthesized as specific inhibitors of the H1 subtype of influenza A viruses. These inhibitors inhibit the pH-induced fusion process, thereby blocking viral entry into host cells. Compound 16 was the most active inhibitor in this series with an EC50 of 0.25 μg/mL in plaque reduction assay. The synthesis and the SAR of these compounds are discussed.