58166-83-9 Usage
Originator
Praxinor,Merck Lipha Sante
Uses
(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.
Manufacturing Process
7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml
isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and
HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of
7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline
hydrochloride was filtered off and dried. MP 243°-244°C.In practice it is usually used as free base.
Check Digit Verification of cas no
The CAS Registry Mumber 58166-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,1,6 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 58166-83:
(7*5)+(6*8)+(5*1)+(4*6)+(3*6)+(2*8)+(1*3)=149
149 % 10 = 9
So 58166-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H23N5O3/c1-12(15(24)13-7-5-4-6-8-13)19-9-10-23-11-20-16-14(23)17(25)22(3)18(26)21(16)2/h4-8,11-12,15,19,24H,9-10H2,1-3H3/t12-,15-/m0/s1