58249-61-9 Usage
Description
6-Benzothiazolecarbonitrie, also known as 6-Cyanobenzothiazol, is an organic compound with the molecular formula C7H4N2S. It is a heterocyclic compound that features a benzene ring fused to a thiazole ring, with a nitrile group attached to the sixth position of the benzene ring. 6-BENZOTHIAZOLECARBONITRILE is known for its chemical reactivity and is widely utilized in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
6-Benzothiazolecarbonitrie is used as a synthetic intermediate for the preparation of heteroaryl carboxylic acids and esters. These compounds are essential in the development of new drugs and pharmaceuticals, as they can be incorporated into the molecular structure of various therapeutic agents. The carboxylation of oxazoles, thiazoles, and oxadiazoles using 6-Benzothiazolecarbonitrie allows for the creation of diverse chemical structures with potential applications in medicine.
Used in Chemical Synthesis:
In the field of organic chemistry, 6-Benzothiazolecarbonitrie serves as a valuable reagent for the synthesis of various heterocyclic compounds. Its unique structure and reactivity make it a versatile building block for the creation of complex organic molecules, which can be further modified and functionalized to achieve desired properties and applications.
Used in Material Science:
6-BENZOTHIAZOLECARBONITRILE's ability to form stable complexes with other molecules makes it a potential candidate for use in the development of new materials with specific properties. For example, 6-Benzothiazolecarbonitrie can be used to create novel polymers, dyes, and pigments with unique characteristics, such as enhanced stability, color, or conductivity.
Check Digit Verification of cas no
The CAS Registry Mumber 58249-61-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,4 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 58249-61:
(7*5)+(6*8)+(5*2)+(4*4)+(3*9)+(2*6)+(1*1)=149
149 % 10 = 9
So 58249-61-9 is a valid CAS Registry Number.
58249-61-9Relevant articles and documents
K2S as Sulfur Source and DMSO as Carbon Source for the Synthesis of 2-Unsubstituted Benzothiazoles
Deng, Guobo,Kuang, Daizhi,Liang, Yun,Yang, Yuan,Yu, Jiangxi,Zhang, Fuxing,Zhu, Xiaoming
supporting information, p. 3789 - 3793 (2020/06/04)
We describe a three-component reaction of o-iodoanilines with K2S and DMSO that provides 2-unsubstituted benzothiazoles in moderate to good isolated yields with good functional group tolerance. Electron-rich aromatic amines and o-phenylenediamines instead of o-iodoanilines provided 2-unsubstituted benzothiazoles and 2-unsubstituted benzimidazoles with and without K2S under similar conditions. Notably, DMSO plays three vital roles: carbon source, solvent, and oxidant.
Method for synthesizing benzothiazole by microwave radiation of benzothioamide compound in aqueous phase
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Paragraph 0013; 0098, (2019/02/13)
The invention discloses a method for synthesizing benzothiazole by microwave radiation of a benzothioamide compound in an aqueous phase. The method includes the steps: adding the benzothioamide compound into the aqueous phase under microwave conditions; performing cyclization under alkaline conditions to generate the benzothiazole. The method for preparing the benzothiazole is environmentally friendly, simple and convenient in operation, safe, cheap and efficient. Compared with the prior art, the method is applicable to a lot of functional groups, high in yield, few in by-products, simple in operation, safe, low in cost and environmentally friendly.
Carbon dioxide as the C1 source for direct C-H functionalization of aromatic heterocycles
Vechorkin, Oleg,Hirt, Nathalie,Hu, Xile
supporting information; experimental part, p. 3567 - 3569 (2010/10/02)
(Equation Presented). A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A good functional group tolerance is achieved.
