58306-30-2 Usage
Chemical Properties
Febantel is White to Off-White Solid
Originator
Rintal, Bayer,W. Germany,1979
Uses
Different sources of media describe the Uses of 58306-30-2 differently. You can refer to the following data:
1. Used as an anthelmintic.
2. Febantel is used as an anthelmintic
Manufacturing Process
2-Amino-5-phenylthiornethoxyacetanilide in methanol solution is heated with
N,N'-bis-methoxycarbonyl-isothiourea-S-methyl ether with the addition of a
catalytic amount of p-toluenesulfonic acid for three hours with stirring under
reflux. The mixture is then filtered hot and after cooling the febantel product
crystallizes out. It is filtered off, rinsed with ether and dried under high
vacuum to give the final product, melting at 129°C to 130°C.
Brand name
Combotel (Bayer AnimalHealth); Negabot Plus Paste (Bayer Animal Health);
Oratel (Bayer Animal Health); Rintal (Bayer Animal
Health).
Therapeutic Function
Anthelmintic
Check Digit Verification of cas no
The CAS Registry Mumber 58306-30-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,3,0 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58306-30:
(7*5)+(6*8)+(5*3)+(4*0)+(3*6)+(2*3)+(1*0)=122
122 % 10 = 2
So 58306-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H22N4O6S/c1-28-12-17(25)21-16-11-14(31-13-7-5-4-6-8-13)9-10-15(16)22-18(23-19(26)29-2)24-20(27)30-3/h4-11H,12H2,1-3H3,(H,21,25)(H2,22,23,24,26,27)
58306-30-2Relevant articles and documents
Febantel, a new broad-spectrum anthelminthic
Wollweber,Koelling,Widdig,Thomas,Schulz,Muermann
, p. 2193 - 2195 (2007/10/13)
N {2 [2,3 Bis (methoxycarbonyl) guanidino] 5 (phenylthio) phenyl } 2 methoxyacetamide (febantel, Rintal) is a new compound which is highly active against various species of nematodes and cestodes in mice, rats, dogs, sheep and cattle. In sheep and cattle a single oral dose of 5 mg/kg resulted in an almost complete elimination of larval and adult intestinal nematodes as well as Dictyocaulus. The compound was well tolerated by all animals tested.
