58344-25-5

Basic information

• Product Name: 1-(2,4-dichlorophenyl)-4,4-dimethylpent-1-en-3-one
• Synonyms: 1-(2,4-dichlorophenyl)-4,4-dimethylpent-1-en-3-one
• CAS NO: 58344-25-5
• Molecular Weight: 257.16
• Mol File: 58344-25-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(2,4-dichlorophenyl)-4,4-dimethylpent-1-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dichlorophenyl)-4,4-dimethylpent-1-en-3-one(58344-25-5)
• EPA Substance Registry System: 1-(2,4-dichlorophenyl)-4,4-dimethylpent-1-en-3-one(58344-25-5)

Safety Data

• Hazardous Substances Data: 58344-25-5(Hazardous Substances Data)

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 1400633-30-8 4-(3-(tert-butyl)-5-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 

Relevant articles and documents

Dehydrozingerone Inspired Discovery of Potential Broad-Spectrum Fungicidal Agents as Ergosterol Biosynthesis Inhibitors

A series of dehydrozingerone derivatives were synthesized, and their fungicidal activities and action mechanism against Colletotrichum musae were evaluated. The bioassay result showed that most compounds exhibited excellent fungicidal activity in vitro at 50 μg mL-1. Compounds 13, 16, 18, 19, and 27 exhibited broad-spectrum fungicidal activity; especially, compounds 19 and 27 were found to have more potent fungicidal activity than azoxystrobin. The EC50 values of compounds 19 and 27 against Rhizoctonia solani were 0.943 and 0.161 μg mL-1 respectively. Moreover, compound 27 exhibited significant in vitro bactericidal activity against Xanthomonas oryzae pv. oryzae, with an EC50 value of 11.386 μg mL-1, and its curative effect (49.64%) and protection effect (51.74%) on rice bacterial blight disease was equivalent to that of zhongshengmycin (42.90%, 40.80% respectively). Compound 27 could also effectively control gray mold (87.10%, 200 μg mL-1) and rice sheath blight (100%, 200 μg mL-1 82.89%, 100 μg mL-1) in vivo. Preliminary action mechanism study showed that compound 27 mainly acted on the cell membrane and significantly inhibited ergosterol biosynthesis in Colletotrichum musae.

Dehydrozingerone derivative and preparation method and application thereof

The invention provides a dehydrozingerone derivative as shown in the description. R-R are each independently selected from hydrogen or halogen or a nitro group or an alkyl group or a substitutedalkoxy group or an alkoxy group or a hydroxyl group; the substituent in the substituted alkoxy group is selected from one or multiple of halogen, a nitro group and a hydroxyl group; R and R areeach independently selected from hydrogen or halogen or nitrogen-containing heterocycle; R is selected from an alkyl group or an alkoxy group or a substituted alkoxy group; the substituent in thesubstituted alkyl group is selected from one or multiple of halogen, a nitro group and a hydroxyl group; X is selected from a hetero atom or a hydroxylamine group. The dehydrozingerone derivative hasbroad-spectrum activity against plant pathogenic fungi and bacteria, and has certain nematicidal activity, and is a lead compound with the broad biological activity.

ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT

The present invention relates to novel triazole compounds of the formulae (I) and (II) as defined below, to agricultural and pharmaceutical compositions containing them and to their use as fungicides, antimycotic, anticancer and antiviral agents.