5851-47-8

Basic information

• Product Name: 1H-Benzimidazole,2-(1-ethylpropyl)-(9CI)
• Synonyms: 1H-Benzimidazole,2-(1-ethylpropyl)-(9CI)
• CAS NO: 5851-47-8
• Molecular Formula: C12H16N2
• Molecular Weight: 188.27
• Product Categories: BENZIMIDAZOLE
• Mol File: 5851-47-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,2-(1-ethylpropyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2-(1-ethylpropyl)-(9CI)(5851-47-8)
• EPA Substance Registry System: 1H-Benzimidazole,2-(1-ethylpropyl)-(9CI)(5851-47-8)

Safety Data

• Hazardous Substances Data: 5851-47-8(Hazardous Substances Data)

Usage

Also known as

Ebastine

Classification

Second-generation, non-sedating antihistamine

Common uses

Treatment of allergic rhinitis and chronic idiopathic urticaria

Mechanism of action

Inhibits the effects of histamine released during an allergic reaction

Symptom relief

Itching, sneezing, and runny nose

Available forms

Tablets and oral solutions

Tolerability

Generally well-tolerated with few side effects

Importance

Valuable tool for managing allergy symptoms and providing relief for individuals with allergic conditions.

Upstream product

• 97-96-1 2-Ethylbutyraldehyde 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Photochemical Synthesis of Benzimidazoles from Diamines and Aldehydes

An efficient, green, cheap, and metal-free photochemical protocol for the synthesis of benzimidazoles has been developed. 2,2-Dimethoxy-2-phenylacetophenone was employed as the photoinitiator and CFL lamps were used as the light source, leading to the cyc

Synthesis of 2-Substituted Benzimidazoles and 1,5-Disubstituted Benzodiazepines on Alumina and Zirconia Catalysts

In this study, alumina, zirconia, manganese oxide/alumina, and manganese oxide/zirconia have been investigated for their catalytic activity in the condensation reaction between o-phenylenediamine and an aldehyde or a ketone to synthesise 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines respectively. Surface area, surface acidity, and morphology of the catalysts have been analysed and correlated with their catalytic activity. The isolated yields of 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines are in the range of 30% to 95%. A good correlation between the amount of surface acid sites as well as the surface morphology of the catalysts and the catalytic activity has been observed. This method has been found to be simple and economical. The solid supports could be regenerated and reused without much loss in their activity. Further, the solid supports have been also found to be effective as general catalysts in the condensation of o-phenylenediamine with other substituted aldehydes and ketones.