59058-14-9Relevant articles and documents
Method for preparing alpha-acyloxy ketone compound
-
Paragraph 0028, (2017/04/28)
The invention discloses a method for preparing an alpha-acyloxy ketone compound. According to the invention, simple and easily available alcohol and carboxylic acid are taken as the raw materials, under mediation of NBS(N-bromo-succinimide) and DBU(1,8-diazabicyclo(5.4.0)undec-7-alkene), the alpha-acyloxy ketone is prepared by a one-pot reaction. The method has the advantages of mild reaction condition, simple and easily available raw materials, wide substrate adaptation scope, no requirement of rigorous reaction conditions such as any metal catalyst, peroxy compounds, low or high temperature and water-free and oxygen-free conditions, metal pollution is avoided; and the method also has the advantages of stable technical condition, simple and safe operation, and easy purifying of the product.
A rapid and facile esterification of na-carboxylates with alkyl halides promoted by the synergy of the combined use of DMSO and an ionic liquid under ambient conditions
Dighe, Satish N.,Bhattad, Ravindra V.,Kulkarni, Raghunath R.,Jain, Kishor S.,Srinivasan, Kumar V.
experimental part, p. 3522 - 3527 (2011/02/22)
The synergy of the combined use of DMSO and an ionic liquid viz. (bbim) has brought about a rapid and efficient esterification of sodium carboxylates with acyl and alkyl halides under ambient conditions in excellent isolated yields (90-95%) in short reaction times (12-40min). Copyright Taylor & Francis Group, LLC.
Organic Reactions in Ionic Liquids: Ionic Liquid-Accelerated Nucleophilic Substitution Reaction of α-Tosyloxyketones with Potassium Salts of Aromatic Acids
Liu, Zhi,Chen, Zhen-Chu,Zheng, Qin-Guo
, p. 33 - 36 (2007/10/03)
The room temperature ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) is used as a 'green' recyclable alternative to classical molecular solvents for the nucleophilic substitution reaction of α-tosyloxy ketones with pota