59108-53-1 Usage
General Description
CHROMAN-3-YLAMINE, also known as 1-amino-2,3-dihydro-1H-indene, is a chemical compound with the molecular formula C9H11NO. It belongs to the class of organic compounds known as chromanes, which are a group of compounds containing a chromane moiety, which consists of a benzene ring fused to an oxygen-containing six-membered aliphatic ring. CHROMAN-3-YLAMINE is commonly used as a building block in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It has also been studied for its potential pharmacological properties, including as an anti-inflammatory and antioxidant agent. Additionally, CHROMAN-3-YLAMINE has been investigated for its potential role in treating neurodegenerative diseases such as Parkinson's and Alzheimer's.
Check Digit Verification of cas no
The CAS Registry Mumber 59108-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,1,0 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 59108-53:
(7*5)+(6*9)+(5*1)+(4*0)+(3*8)+(2*5)+(1*3)=131
131 % 10 = 1
So 59108-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO/c10-8-5-7-3-1-2-4-9(7)11-6-8/h1-4,8H,5-6,10H2/t8-/m1/s1
59108-53-1Relevant articles and documents
Asymmetric amination of tetralone and chromanone derivatives employing ω-transaminases
Pressnitz, Desiree,Fuchs, Christine S.,Sattler, Johann H.,Knaus, Tanja,Macheroux, Peter,Mutti, Francesco G.,Kroutil, Wolfgang
, p. 555 - 559 (2013)
Various (S)-selective and (R)-selective ω-transaminases were investigated for the amination of 1- and 2-tetralone and derivatives as well as of 3- and 4-chromanone. All ketones tested were aminated to give the corresponding enantiopure amines (ee > 99%) employing at least one of the enzymes investigated. In most of the cases the (S)- as well as the (R)-enantiomer was obtained in optically pure form. The amination of 3-chromanone was performed on a 100 mg scale leading to optically pure (R)-3-aminochromane (ee > 99%) with complete conversion and 78% isolated yield.
