59276-09-4 Usage
Natural product
Cularine is a natural product isolated from the plant genus Stephania.
Chemical class
It belongs to the isoquinoline alkaloids, a group of naturally occurring organic compounds.
Antifungal
It exhibits antifungal properties, which can be useful in treating fungal infections.
Antibacterial
It has antibacterial properties, which can help in combating bacterial infections.
Antitumor
It demonstrates antitumor properties, making it a potential candidate for cancer research and treatment.
Chemical structure
The compound's structure consists of a benzyl group connected to the isoquinoline ring, with two methoxy groups on the benzene ring and two on the isoquinoline ring.
Medicinal chemistry research
Cularine has shown potential in medicinal chemistry research, particularly in the development of new drug candidates.
Therapeutic applications
Due to its pharmacological activities, Cularine is being explored for various therapeutic applications, including treatments for infections and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 59276-09-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,2,7 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 59276-09:
(7*5)+(6*9)+(5*2)+(4*7)+(3*6)+(2*0)+(1*9)=154
154 % 10 = 4
So 59276-09-4 is a valid CAS Registry Number.
59276-09-4Relevant articles and documents
Coralyne analogs as topoisomerase inhibitors
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, (2008/06/13)
The present invention provides protoberberine alkaloid derivatives useful as anticancer agents, and methods of use thereof. The invention also provides protoberberine derivatives useful as topoisomerase inhibitors. The invention further provides coralyne and nitidine derivatives which are topoisomerase I-targeted therapeutics effective against camptothecin resistant cancer cells, and are especially effective against CNS tumors.
