59483-54-4

Basic information

• Product Name: 3-Chloro-2-nitroaniline
• Synonyms: TIMTEC-BB SBB008617;3-CHLORO-2-NITRO-PHENYLAMINE;3-CHLORO-2-NITROANILINE;3-CHLORO-2-NITROANILINE ---YELLOW POWDER, 98%---;2-Nitro-3-chloroaniline;3-Chloro-2-nitroaniline 98%;2-Amino-6-chloronitrobenzene, 1-Amino-3-chloro-2-nitrobenzene;2-Amino-6-chloronitrobenzene
• CAS NO: 59483-54-4
• Molecular Formula: C₆H₅ClN₂O₂
• Molecular Weight: 172.57
• EINECS: 261-782-9
• Product Categories: Amines;blocks;NitroCompounds;Pyridines;Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 59483-54-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 107-108°C
• Boiling Point: 327.1 °C at 760 mmHg
• Flash Point: 151.6 °C
• Appearance: /
• Density: 1.494 g/cm³
• Vapor Pressure: 0.000207mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -1.29±0.10(Predicted)
• CAS DataBase Reference: 3-Chloro-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-2-nitroaniline(59483-54-4)
• EPA Substance Registry System: 3-Chloro-2-nitroaniline(59483-54-4)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 59483-54-4(Hazardous Substances Data)

Usage

Chemical Properties

red powder

InChI:InChI=1/C6H5ClN2O2/c7-4-2-1-3-5(8)6(4)9(10)11/h1-3H,8H2

Upstream product

• 5228-61-5 5-bromo-2-nitroaniline 
• 588-07-8 3-Chloroacetanilide 
• 7647-01-0 hydrogenchloride 
• 602-02-8 2,3-dinitrochlorobenzene 
• 54381-48-5 C₆H₅ClN₂O₂ 
• 601-88-7 2,6-dichloronitrobenzene 
• 4771-47-5 3-chloro-2-nitro-benzoic acid 
• 59772-47-3 3-chloro-2-nitrobenzamide 
• 99233-27-9 N-(3-chloro-2-nitrophenyl)acetamide 
• 124-41-4 sodium methylate 
• 64-17-5 ethanol 
• 19088-99-4 3-chloro-2-nitrobenzoyl chloride 

Downstream Products

• 1000573-99-8 4-bromo-3-chloro-2-nitro aniline 
• 1449690-59-8 C₁₅H₂₁ClN₂O₃ 
• 60498-57-9 3-chloro-N-methyl-2-nitroaniline 
• 141816-10-6 3-chloro-2-nitro-N,N-dimethylaniline 
• 1357159-32-0 4-bromo-3-chloro-N₁-methylbenzene-1,2-diamine 
• 1357159-31-9 4-bromo-3-chloro-N-methyl-2-nitroaniline 
• 1421785-37-6 2-methoxy-N-[3-(methylthio)-2-nitrophenyl]acetamide 
• 1616950-80-1 N-(5-(3-(4-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-2-phenylacetamide 
• 1616950-82-3 N-(5-(3-(4-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-5-yl)pyridin-3-yl)-2-phenylacetamide 
• 1568917-15-6 C₂₃H₂₇N₃O₂ 
• 1568916-46-0 C₁₅H₁₄N₂ 
• 1568917-10-1 C₂₁H₂₅N₃O 
• 1568916-86-8 C₂₁H₁₉N₅O 

Relevant articles and documents

NRF2 REGULATORS

The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.

Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles

(Chemical Equation Presented) A series of 47 novel N1-alkylated- 2-aryl-5(6)-substituted-1H-benzimidazoles and their three novel indole analogues were synthesized and evaluated for in vitro antifungal activities against Candida species by the tube dilution method. The results showed that compounds 79 and 80, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25-3.12 μg/mL. Indole analogues 108-110 have no inhibitory activity.

C-6 ring-substituted pyrido[1,2-a]benzimidazole derivatives useful in treating central nervous system disorders

A C-6 ring-substituted pyrido[1,2-a]benzimidazole derivative of the formula: methods of preparation and pharmaceutical compositions containing a substituted pyrido[1,2-a]benzimidzole derivative as the active ingredient are disclosed. The substituted pyrido[1,2-a]benzimidazole derivatives are useful in the treatment of central nervous system disorders.