59488-39-0

Basic information

• Product Name: Ethane, 1,1,1-trifluoro-2-isothiocyanato-
• CAS NO: 59488-39-0
• Molecular Formula: C3H2F3NS
• Molecular Weight: 141.117
• Mol File: 59488-39-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethane, 1,1,1-trifluoro-2-isothiocyanato-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethane, 1,1,1-trifluoro-2-isothiocyanato-(59488-39-0)
• EPA Substance Registry System: Ethane, 1,1,1-trifluoro-2-isothiocyanato-(59488-39-0)

Safety Data

• Hazardous Substances Data: 59488-39-0(Hazardous Substances Data)

Usage

General Description

Ethane, 1,1,1-trifluoro-2-isothiocyanato- is a chemical compound with the molecular formula C3H3F3NS. It is a colorless gas that is used as a reagent in organic synthesis. Ethane, 1,1,1-trifluoro-2-isothiocyanato- is primarily known for its use in the production of a wide range of pharmaceuticals and agrochemicals. It is also used as a solvent and as a raw material in the manufacturing of various industrial products. Its unique chemical properties make it a valuable tool for chemical research and development. Additionally, it is important to handle this compound with care, as exposure to high concentrations can be harmful to human health.

Upstream product

• 75-15-0 carbon disulfide 
• 753-90-2 trifluoroethylamine 

Relevant articles and documents

Preparation method of trifluoroisothiocyanate ethane

The invention relates to a preparation method of trifluoroisothiocyanate ethane. The preparation method comprises the steps of 1, mixing trifluoroethylamine, triethylamine and a solvent to obtain a first reaction mixture; controlling the temperature to be 10-12 DEG C, adding carbon disulfide, and reacting at the temperature of 5-20 DEG C to obtain a second reaction mixture containing trifluoroethylamino thioformate, wherein the molar ratio of the trifluoroethylamine to the triethylamine is 1: (1.05-2), the molar ratio of trifluoroethylamine to carbon disulfide is 1: (1-1.2), the molar ratio of trifluoroethylamine to the solvent is 1: (5-8), and the solvent is toluene, xylene or dichloromethane; 2, cooling the second reaction mixture obtained in the step 1 to 5-10 DEG C, adding solid light, stirring at room temperature, heating to the temperature of 35-45 DEG C, and reacting to obtain a trifluoroisothiocyanate ethane mixture; and then cooling, adding water and rectifying to obtain trifluoroisothiocyanate ethane. Compared with the prior art, the method has the advantages of high product yield and less three wastes by adopting solid light as a catalyst. According to the method, toluene/dichloromethane is adopted as the solvent, the problems that tetrahydrofuran and water are mixed and dissolved, part of products are brought into a water phase, the reaction yield is too low, and the solvent is difficult to recover are solved, the solvent can be recovered and reused after being evaporated, the recovery rate reaches 88% or above, the reaction cost is reduced, and emission of three wastes is reduced.