595-48-2Relevant articles and documents
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Brunner
, (1894)
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Oxidation of methylmalonic acid by cerium(IV). Evidence for parallel reaction pathways
Kvernberg, Per Olav,Hansen, Eddy W.,Pedersen, Bjorn,Rasmussen, Asbjorn,Ruoff, Peter
, p. 2327 - 2331 (2007/10/03)
The reaction between methylmalonic acid (MeMA) and Ce(IV) ion in 1 M sulfuric acid/D2SO4 has been studied by means of 1H- and 13C-NMR. When MeMA is in excess, acetic acid, hydroxymethylmalonic acid, and pyruvic acid are formed as stable end products. When Ce(IV) is in stoichiometric excess, acetic acid is the only product. Approximately 70-80% of the MeMA forms rapidly acetic acid with hydroxymethylmalonic acid and pyruvic acid as reactive intermediates. The remaining MeMA reacts along parallel pathways and forms two intermediates, which slowly convert to hydroxymethylmalonic acid and pyruvic acid, respectively.
Process for preparing alkyl esters of methyltartronic acid
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, (2008/06/13)
There is described a process for preparing alkyl esters of methyltartronic acid by hydroxylation of methacrylic acid to alpha-methylglyceric acid with H2 O2, in an aqueous medium, in the presence of H2 WO4 and optionally of H3 PO4 or H3 AsO4 or alkaline salts thereof as catalysts, at pH3 in excess or with O2, in an aqueous-alkaline medium, in the presence of Pd or Pt carried on carbon or oxides thereof as catalysts, at temperatures of 60°-100° C., and final esterification of methyltartronic acid with alcohols C1 -C4.
