597542-74-0

Basic information

• Product Name: Cudraflavanone B
• Synonyms: Cudraflavanone B
• CAS NO: 597542-74-0
• Molecular Formula: C20H20O6
• Molecular Weight: 356.37
• Mol File: 597542-74-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cudraflavanone B(CAS DataBase Reference)
• NIST Chemistry Reference: Cudraflavanone B(597542-74-0)
• EPA Substance Registry System: Cudraflavanone B(597542-74-0)

Safety Data

• Hazardous Substances Data: 597542-74-0(Hazardous Substances Data)

Usage

General Description

Cudraflavanone B is a chemical compound found in the stem bark of the plant Zanthoxylum tingoassuiba. It belongs to the class of compounds known as flavanones and exhibits various bioactivities, including antioxidant, anti-inflammatory, and anti-cancer properties. Cudraflavanone B has been found to inhibit the growth of cancer cells in vitro and has potential for use in the development of novel anticancer drugs. Additionally, it has shown promising effects in reducing inflammation and oxidative stress, making it a potential candidate for the treatment of various inflammatory diseases. Furthermore, Cudraflavanone B may have applications in the food and cosmetic industries due to its antioxidant properties. Overall, research on Cudraflavanone B suggests its potential as a therapeutic agent with diverse biomedical applications.

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Relevant articles and documents

Regio- and stereospecific prenylation of flavonoids by Sophora flavescens prenyltransferase

Prenylflavonoids are valuable natural products that are widely distributed in plants. They often possess divergent biological properties, including phytoestrogenic, anti-bacterial, anti-tumor, and anti-diabetic activities. The reaction catalyzed by prenyltransferases represents a Friedel-Crafts alkylation of the flavonoid skeleton in the biosynthesis of natural prenylflavonoids and often contributes to the structural diversity and biological activity of these compounds. However, only a few plant flavonoid prenyltransferases have been identified thus far, and these prenyltransferases exhibit strict substrate specificity and low catalytic efficiency. In this article, a flavonoid prenyltransferase from Sophora flavescens, SfFPT, has been identified that displays high catalytic efficiency with high regiospecificity acting on C-8 of structurally different types of flavonoid (i.e., flavanone, flavone, flavanonol, and dihydrochalcone, etc.). Furthermore, SfPFT exhibits strict stereospecificity for levorotatory flavanones to produce (2S)-prenylflavanones. This study is the first to demonstrate the substrate promiscuity and stereospecificity of a plant flavonoid prenyltransferase in vitro. Given its substrate promiscuity and high catalytic efficiency, SfFPT can be used as an environmentally friendly and efficient biological catalyst for the regio- and stereospecific prenylation of flavonoids to produce bioactive compounds for potential therapeutic applications. Copyright