59846-49-0Relevant articles and documents
Efficient synthesis of highly substituted pyrrolin-4-ones via PIFA-mediated cyclization reactions of enaminones
Huang, Jie,Liang, Yongjiu,Pan, Wei,Yang, Yang,Dong, Dewen
, p. 5345 - 5348 (2008/09/17)
A convenient and efficient synthesis of highly substituted pyrrolin-4-ones is developed via the PIFA-mediated cyclization reactions of readily available enaminones, and a mechanism involving sequential cleavage of N - C bond, formation of new N - C bond, intramolecular addition reaction, and benzilic acid type rearrangement is proposed.