59964-94-2

Basic information

• Product Name: BIPHENYL-2-YL-HYDRAZINE
• Synonyms: BIPHENYL-2-YL-HYDRAZINE
• CAS NO: 59964-94-2
• Molecular Formula: C₁₂H₁₂N₂
• Molecular Weight: 184.24
• Mol File: 59964-94-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 167 °C(Press: 4 Torr)
• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.06±0.10(Predicted)
• CAS DataBase Reference: BIPHENYL-2-YL-HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: BIPHENYL-2-YL-HYDRAZINE(59964-94-2)
• EPA Substance Registry System: BIPHENYL-2-YL-HYDRAZINE(59964-94-2)

Safety Data

• Hazardous Substances Data: 59964-94-2(Hazardous Substances Data)

Usage

General Description

BIPHENYL-2-YL-HYDRAZINE, also known as diphenylhydrazine, is an organic compound with the chemical formula C12H12N2. It is a clear yellow to light brown liquid with a pungent odor. BIPHENYL-2-YL-HYDRAZINE is commonly used as an intermediate in the production of pharmaceuticals and dyes. It is also used in the synthesis of other organic compounds and as a reagent in chemical reactions. However, it is known to be toxic and poses health risks if ingested, inhaled, or comes into contact with the skin. It is important to handle and store this chemical with caution and adhere to proper safety procedures when working with it.

Upstream product

• 52500-12-6 biphenyl-2-diazonium ; chloride 
• 2051-60-7 2-chloro-1,1'-biphenyl 
• 90-41-5 2-phenylaniline 

Downstream Products

• 75600-96-3 ethyl (4-methoxyphenyl)glyoxylate 2-phenylphenylhydrazone 
• 1246200-12-3 ethyl 1-(biphenyl-2-yl)-5-methylpyrazole-3-carboxylate 
• 230-17-1 benzo[c]cinnoline 
• 84-15-1 o-terphenyl 
• 149877-65-6 N'-Biphenyl-2-yl-hydrazinecarboxylic acid cyclopentyl ester 

Relevant articles and documents

Palladium-catalyzed cross-coupling of aryl chlorides and tosylates with hydrazine

Hydrazine is not a problem anymore: The title transformation is the first reaction to yield aryl hydrazines through the cross-coupling of aryl chlorides and tosylates with hydrazine. An appropriately designed palladium catalyst allows this reaction to proceed rapidly under mild conditions, and with excellent chemoselectivity (see scheme; Ad=adamantyl, Ts=4-toluenesulfonyl).

Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides

Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.