60131-32-0

Basic information

• Product Name: Benzeneacetaldehyde, 3-benzoyl-a-methyl-
• CAS NO: 60131-32-0
• Molecular Formula: C16H14O2
• Molecular Weight: 238.286
• Mol File: 60131-32-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, 3-benzoyl-a-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, 3-benzoyl-a-methyl-(60131-32-0)
• EPA Substance Registry System: Benzeneacetaldehyde, 3-benzoyl-a-methyl-(60131-32-0)

Safety Data

• Hazardous Substances Data: 60131-32-0(Hazardous Substances Data)

Upstream product

• 74626-57-6 2-(3-(2-phenyl-1,3-dioxolan-2-yl)phenyl)propanal 

Downstream Products

• 1173289-23-0 (2S)-[3-(2-hydroxy-1-methyl-ethyl)-phenyl]-phenyl-methanone 
• 114937-08-5 (4R)-2-[1-(3-benzoylphenyl)-ethyl]-thiazolidine-4-carboxylic acid hydrochloride 

Relevant articles and documents

Chemoenzymatic synthesis of (2S)-2-arylpropanols through a dynamic kinetic resolution of 2-arylpropanals with alcohol dehydrogenases

We applied Horse Liver Alcohol Dehydrogenase (HLADH) to the enantioselective synthesis of six (2S)-2-arylpropanols, useful intermediates in the synthesis of Profens. The influence of substrate structure and reaction conditions on yields and enantioselectivity were investigated. The high yields and high enantioselectivity towards the (S)-enantiomer obtained in the bioreduction of 2-arylpropionic aldehydes, clearly indicate the achievement of a DKR process through a combination of an enzyme-catalyzed kinetic reduction with a chemical base-catalyzed racemization of the unreacted aldehydes. The racemization step is represented by the keto-enol equilibrium of the aldehyde and can be controlled by modulating pH and reaction conditions.

Synthesis of aldehydes from carboxylic acids via N-methoxyimidoyl bromides: Deoximation of O-methyloximes

Aldehydes are synthesized by hydrogenation and subsequent deoximation of substituted N-methoxyalkanimidoyl bromides, which are prepared in one pot by reaction of the corresponding carboxylic acids with methoxyamine and triphenylphosphine carbon tetrabromide. Regeneration of aldehydes and ketones from O-methyloximes under mild conditions is also described.

Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid

Compounds of formula in which R, R1 and Y have the meanings shown in the description, their preparation by condensing an aldehyde or a ketone with cysteine or a derivative thereof and their use in the pharmaceutical field. The compounds of formula I possess antipyretic, anti--inflammatory, mucolytic and analgesic activity together with a low capacity to cause gastric injuries. The compounds of formula I, furthermore, are particularly useful in the treatment of ischemia and reperfusion syndromes.