601512-75-8Relevant articles and documents
MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
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, (2021/02/19)
The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.
xylo-configured oligonucleotides (XNA, xylo nucleic acids): Synthesis and hybridization studies
Poopeiko, Nicolai E.,Dahl, Britta M.,Wengel, Jesper
, p. 1147 - 1149 (2007/10/03)
We report synthesis and high-affinity hybridization of fully modified home-thymine 2′-deoxy and 2′-deoxy-2′-fluoro xylo nucleic acids.