60293-41-6

Basic information

• Product Name: Benzenemethanamine, N-(3-phenyl-2-propenylidene)-
• CAS NO: 60293-41-6
• Molecular Formula: C16H15N
• Molecular Weight: 221.302
• Mol File: 60293-41-6.mol
• Article Data: 41

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(3-phenyl-2-propenylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(3-phenyl-2-propenylidene)-(60293-41-6)
• EPA Substance Registry System: Benzenemethanamine, N-(3-phenyl-2-propenylidene)-(60293-41-6)

Safety Data

• Hazardous Substances Data: 60293-41-6(Hazardous Substances Data)

Upstream product

• 1885-38-7 cinnamic nitrile 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 100-46-9 benzylamine 
• 52826-45-6 (benzylimino)triphenylphosphorane 
• 104-55-2 3-phenyl-propenal 
• 104-54-1 3-Phenylpropenol 
• 14371-10-9 (E)-3-phenylpropenal 
• 100-47-0 benzonitrile 
• 57152-94-0 N-benzylcinnamamide 
• 62-53-3 aniline 
• 622-79-7 benzyl azide 
• 27046-29-3 N-(4-bromobenzylidene)benzylamine 
• 1361111-11-6 C₁₆H₁₃⁽²⁾H₂BrN₂ 
• 1361110-35-1 methyl 3-(benzylamino)-2,2-dideutero-3-(4-bromophenyl)propanoate 

Downstream Products

• 77499-91-3 (E+Z)-N-benzyl-9-phenyl-11-undecatetraene-1,3,6,10 
• 23652-86-0 (Z)-4-(benzylamino)-3-penten-2-one 
• 174090-38-1 Cr(CO)5(C₆H₅)3(CH₃)(OCH₃)C₆H₂N 
• 1058138-86-5 1-benzyl-4-methylene-2-styrylpyrrolidine 
• 1361111-17-2 C₁₈H₁₆⁽²⁾H₂N₂ 
• 1016970-59-4 C₂₂H₂₅N 
• 1360452-22-7 C₂₂H₂₇N 
• 124994-82-7 (S)-1-Benzyl-3-ethyl-3-phenylsulfanyl-4-((E)-styryl)-azetidin-2-one 
• 173416-02-9 (E)-N-benzyl-1-phenylhexa-1,5-dien-3-amine 

Relevant articles and documents

Synthesis of β-Phosphinolactams from Phosphenes and Imines

Various cis-β-phosphinolactams are synthesized stereoselectively for the first time from imines and diazo(aryl)methyl(diaryl)phosphine oxides under microwave irradiation. Diazo(aryl)methyl(diaryl)phosphine oxides first undergo the Wolf rearrangement to generate phosphenes. Imines nucleophilically attack the phosphenes followed by an intramolecular nucleophilic addition via less steric transition states to give final cis-β-phosphinolactams. C-Styrylimines generally give rise to β-phosphinolactams in higher yields than C-arylimines. The stereoselectivity and proposed mechanism are rationalized by DFT theoretical calculation.

Periselectivity in the aza-Diels–Alder reaction of 1-azadienes with α-oxoketenes: A combined experimental and theoretical study

Inversions in the periselectivity of formal aza-Diels–Alder cycloadditions between α-oxoketenes generated by a thermally-induced Wolff rearrangement and 1-azadienes were observed experimentally as a function of the α-oxoketene and the 1-azadiene, as well as the reaction temperature and time. Some unexpected inversion in the diastereoselectivity was observed, too. These variations in selectivities were fully rationalized by computational modeling using density functional theory (DFT) methods.

Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions

A series of 1,1′-spirobiindane-7,7′-diol (SPINOL) analogues bearing a 2,2′-dimethyl-, cyclopentyl-, or cyclohexyl-fused ring were synthesized, and their distinct structural features were elucidated by X-ray crystallography. On the basis of these scaffolds, chiral monophosphoramidite ligands 6 a–m were synthesized, which demonstrated excellent enantioselectivity in RhI-catalyzed asymmetric hydrogenation of a dehydro amino acid methyl ester. Ligands 6 a–m were also successfully applied in the RhI-catalyzed enantioselective [4+2] cycloaddition of α,β-unsaturated imines with isocyanates, which afforded the corresponding pyrimidinones in good yields (60–92 %) with high enantioselectivities (75–92 % ee).