603122-78-7

Basic information

• Product Name: methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
• Synonyms: methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate;(2-CHLORO-4-(METHOXYCARBONYL)PHENYL)BORONIC ACID PINACOL ESTER
• CAS NO: 603122-78-7
• Molecular Formula: C₁₄H₁₈BClO₄
• Molecular Weight: 296.55432
• Mol File: 603122-78-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(603122-78-7)
• EPA Substance Registry System: methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(603122-78-7)

Safety Data

• Hazardous Substances Data: 603122-78-7(Hazardous Substances Data)

Usage

Description

Methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a chemical compound with the molecular formula C15H17BO4Cl. It is a methyl ester of 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid. methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is known for its role as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.

Uses

Used in Organic Synthesis:
Methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a building block in organic synthesis for the production of pharmaceuticals and agrochemicals. Its unique structure allows it to be a versatile intermediate in the synthesis of various biologically active compounds.
Used in Cross-Coupling Reactions:
In the field of organic chemistry, methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a reagent in cross-coupling reactions to form carbon-carbon bonds. This application is crucial for creating complex molecular structures that are essential in the development of new drugs and agrochemicals.
Used in Research and Industrial Processes:
Methyl 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a valuable chemical reagent with a wide range of applications in both research and industrial processes. Its utility in creating new compounds and contributing to the advancement of chemical synthesis makes it an important component in the field of chemistry.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 155884-04-1 3-chloro-4-trifluoromethanesulfonyloxy-benzoic acid methyl ester 
• 99-76-3 methyl 4-hydroxylbenzoate 

Downstream Products

• 1621254-65-6 methyl 5'-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)-4,4-dimethylcyclohex-1-enyl)-2-chloro-2'-fluoro-4'-methoxybiphenyl-4-carboxylate 

Relevant articles and documents

Multicomponent multicatalyst reactions (MC)2R: One-pot synthesis of 3,4-dihydroquinolinones

A Rh/Pd/Cu catalyst system led to an efficient synthesis of dihydroquinolinones in one-pot, two operations. The reaction features the first triple metal-catalyzed transformations in one reaction vessel, without any intermediate workup. The conjugate-addition/amidation/amidation reaction sequence is highly modular, divergent, and practical.

AMINOALCOHOL DERIVATIVES

The present invention relates to a compound formula [I]: wherein Y is bond,--O--(CH2)n--(in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, R4 is hydrogen or lower alkyl, R5 and R8 are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R6 is hydrogen, lower alkyl, etc., R9 is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.