60319-07-5

Basic information

• Product Name: 2 6-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&
• Synonyms: 2 6-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&;2,6-Dimethoxyphenyl trifluoromethanesulfonate 97%
• CAS NO: 60319-07-5
• Molecular Formula: C₉H₉F₃O₅S
• Molecular Weight: 286.225
• Product Categories: Organic Building Blocks;Organic Triflates;Sulfur Compounds;Organic Triflates;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfur Compounds
• Mol File: 60319-07-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 115 °C0.2 mm Hg(lit.)
• Flash Point: 207 °F
• Appearance: /
• Density: 1.376 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000212mmHg at 25°C
• Refractive Index: n20/D 1.4630(lit.)
• CAS DataBase Reference: 2 6-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(CAS DataBase Reference)
• NIST Chemistry Reference: 2 6-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(60319-07-5)
• EPA Substance Registry System: 2 6-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(60319-07-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 60319-07-5(Hazardous Substances Data)

Usage

Physical properties

Colorless, crystalline solid

Solubility

Soluble in organic solvents such as dichloromethane and acetonitrile

Use

Reagent in organic synthesis for protection of alcohols and phenols, building block in the synthesis of pharmaceuticals and agrochemicals, preparation of intermediates and advanced materials for manufacturing polymers and electronics

Stability

Stable under normal conditions

Safety precautions

Potential irritant effects on skin, eyes, and respiratory system, handle with care and caution.

InChI:InChI=1/C9H9F3O5S/c1-15-6-4-3-5-7(16-2)8(6)17-18(13,14)9(10,11)12/h3-5H,1-2H3

Upstream product

• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 21897-50-7 1,3-dimethoxy-2-vinylbenzene 
• 128920-00-3 2,6-dimethoxy-1-(2-phenylethynyl)benzene 
• 3698-35-9 1,3-dimethoxy-2-(2-propenyl)benzene 
• 5673-07-4 2,6-dimethoxytoluene 
• 151-10-0 1,3-Dimethoxybenzene 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 16932-45-9 1-bromo-2,6-dimethoxybenzene 
• 52856-19-6 1-(2,6-dimethoxyphenyl)-2-phenylethanone 
• 1466-76-8 2-6-dimethoxybenzoic acid 
• 851231-30-6 1,3-dimethoxy-2-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolanyl)-benzene 

Relevant articles and documents

The conversion of phenols to the corresponding aryl halides under mild conditions

Mild, novel procedures have been developed for the syntheses of aryl halides from the corresponding phenols in modest to good yields via boronate ester intermediates.

Deoxygenation of Highly Hindered Phenols

Highly hindered phenolic compounds can be efficiently deoxygenated by reduction of the corresponding triflates under homogeneous or heterogeneous (Pd/C) conditions.Reductive deoxygenation under homogeneous conditions has been shown to occur both in the presence of acid (HCOOH, CH3COOH, (CH3)3CCOOH, PhCH2COOH) or in its absence.The concomitant formation of dibutylformamide apparently derives from aminolysis of DMF by dibutylamine, the Pd(0)-catalyzed hydrolysis product of tributylamine.Deuteration experiments suggest that several hydrogen (or deuterium) sources operate in the hydrogenolysis processes studied.