6045-08-5

Basic information

• Product Name: 2-AMINO-2-METHYL-D3-PROPANE-1,1,1,3,3,3-D6
• Synonyms: TERT-BUTYL-D9-AMINE;TERT-BUTYL-D9-AMINE, 98 ATOM % D;2-Propan-1,1,1,3,3,3-d6-amine, 2-(methyl-d3)-;Tert-Butylamine-D9;2-AMINO-2-METHYL-D3-PROPANE-1,1,1,3,3,3-D6;2-AMINO-2-METHYL-D3-PROPANE-D6
• CAS NO: 6045-08-5
• Molecular Formula: C₄H₁₁N
• Molecular Weight: 82.19
• Product Categories: 13C & 2H Sugars
• Mol File: 6045-08-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: -67 °C(lit.)
• Boiling Point: 46 °C(lit.)
• Flash Point: 16 °F
• Appearance: /
• Density: 0.780 g/mL at 25 °C
• Vapor Pressure: 2.01E-07mmHg at 25°C
• Refractive Index: n20/D 1.401(lit.)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: 2-AMINO-2-METHYL-D3-PROPANE-1,1,1,3,3,3-D6(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-2-METHYL-D3-PROPANE-1,1,1,3,3,3-D6(6045-08-5)
• EPA Substance Registry System: 2-AMINO-2-METHYL-D3-PROPANE-1,1,1,3,3,3-D6(6045-08-5)

Safety Data

• Hazard Codes: F,C
• Statements: 11-20/22-35
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3286 3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 6045-08-5(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Oil

Uses

tert-Butylamine is common reagent in pharmaceuticals syntheses. Used in the preparation of aminoBODIPY compounds for chemical analyses. Also it aids in the synthesis of benzylurea-based insecticides c ontaining amide and sulfonate groups. It has also been used in the synthesis of BPTES analogs, that act as glutaminase inhibitors, which can attenuate the growth of human lymphoma B cells. This is the labeled analog.

InChI:InChI=1/C15H18N4O3/c1-4-5-14-13(10-17(2)3)15(20)18(16-14)11-6-8-12(9-7-11)19(21)22/h6-10H,4-5H2,1-3H3/b13-10-

Upstream product

• 25725-11-5 [D₉]-tert-butyl alcohol 

Downstream Products

• 1246819-58-8 D₉-mabuterol 
• 1246819-04-4 D₉-cimbuterol 
• 1184922-65-3 (R)-2-((tert-butyl-d9)amino)-1-(3-chlorophenyl)-2-d1-propan-1-one, deuterium chloride salt 
• 52168-52-2 2-Methyl-2-nitropropane-d9 

Relevant articles and documents

Electron Spin Resonance Spin-Trapping Analysis of γ-Induced Radicals in Polycrystalline α-D-Glucose

γ-Induced radicals in polycrystalline α-D-glucose are trapped with a water-ethanol solution of 2-nitroso-2-methylpropane.Five long-lived nitroxide spin-adducts are evidenced by electron spin resonance (ESR).Specifically labeled glucoses are also studied.Tentative assignments are discussed for each nitroxide radical.

A stable isotope labeled β receptor agonist synthetic method of compound

The invention relates to a synthesis method of a stable isotope-labeled beta receptor agonist type compound. The synthesis method comprises the following steps: (1) by taking stable isotope-labeled methanol as a raw material, reacting with acetone or stable isotope-labeled acetone, and ammonifying to obtain stable isotope-labeled tert-butylamine; and (2) by taking a bromoketone type compound as a precursor of the beta receptor agonist type compound, reacting with stable isotope-labeled tert-butylamine to prepare the stable isotope-labeled beta receptor agonist type compound. Compared with the prior art, the method for preparing the stable isotope-labeled beta receptor agonist, provided by the invention, is simple, safe and reliable, the chemical purity of the product after separation and purification is above 99.0%, the isotopic abundance is above 98.0% atom, and the product can fully meet the requirements of residual detection in the field of food safety.