60575-19-1

Basic information

• Product Name: CHROMAN-3-YLAMINE
• Synonyms: 3,4-dihydro-3-amino-2H-1-benzopyran;CHROMAN-3-YLAMINE;CHROMAN-3-AMINE;3,4-dihydro-2H-chroMen-3-aMine;3,4-Dihydro-2H-1-benzopyran-3-amine;3-Aminochroman;2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-
• CAS NO: 60575-19-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Mol File: 60575-19-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 256.8 °C at 760 mmHg
• Flash Point: 117.9 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.0151mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: CHROMAN-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: CHROMAN-3-YLAMINE(60575-19-1)
• EPA Substance Registry System: CHROMAN-3-YLAMINE(60575-19-1)

Safety Data

• Hazardous Substances Data: 60575-19-1(Hazardous Substances Data)

Usage

General Description

CHROMAN-3-YLAMINE is a chemical compound that belongs to the family of chromans, and it is specifically classified as a chroman-3-ylamine. It is a nitrogen-containing compound with a chroman core structure and an amine functional group, with the chemical formula C10H11NO. CHROMAN-3-YLAMINE has potential applications in medicinal chemistry and drug discovery, as it can serve as a building block for the synthesis of various biologically active molecules. Additionally, chroman-3-ylamine derivatives have been studied for their potential pharmacological activities, including anti-inflammatory and antitumor properties. Overall, CHROMAN-3-YLAMINE is a versatile chemical with promising prospects for pharmaceutical research and development.

InChI:InChI=1/C9H11NO/c10-8-5-7-3-1-2-4-9(7)11-6-8/h1-4,8H,5-6,10H2

Upstream product

• 19090-04-1 chroman-3-one 
• 22649-28-1 2H-chromene-3-carboxylic acid 
• 57543-66-5 2H-chromene-3-carbonitrile 
• 90-02-8 salicylaldehyde 
• 18518-71-3 3-aminochroman hydrochloride 
• 92210-53-2 3-nitro-2H-1-benzopyran 
• 153167-33-0 3-nitro-3,4-dihydro-2H-1-benzopyrane 
• 1034770-39-2 chroman-3-one O-methyl oxime 

Relevant articles and documents

POTENT SMALL MOLECULE INHIBITORS OF AUTOPHAGY, AND METHODS OF USE THEREOF

Certain aspects of the invention relate to small molecule autophagy inhibitors, and their use for treatment and prevention of cancers and acute pancreatitis. Medicinal chemistry studies led to small molecular autophagy inhibitors with improved potency and selectivity.

Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof

Compounds that are antagonists of the VR1 receptor, having formula (I) [image] or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.

3,4-Dihydro-3-amino-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. 1. Synthesis and Structure-Activity Relationship Studies

A series of 3,4-dihydro-3-amino-2H-1-benzopyran derivatives were prepared in order to determine the necessary structural requirements for good affinity for 5-HT1A receptors and high selectivity versus other receptors.Modifications of the extrac