60577-30-2Relevant articles and documents
A iodo phenol preparation method
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Paragraph 0035-0041, (2019/06/07)
The invention relates to a preparation method of iodo phenol, specific steps are as follows: (1) will be benzenes boric acid, potassium iodide is added in the methanol solution mixing, slowly adding the oxidizing agent, to get the crude product after the reaction; (2) the step (1) of the crude product by washing, after separation and purification, to obtain the iodo phenol. Compared with the prior art, the preparation method of this invention has a region of high selectivity, the substrate can be expanded is good, the preparation process is simple, convenient operation and the like.
Selectivity enhancement of aromatic halogenation reactions at the micellar interface: Effect of highly ionic media
Samant, Bhupesh S.,Bhagwat, Sunil S.
scheme or table, p. 1039 - 1044 (2012/10/18)
Halogenation (iodination and bromination) of various aromatic compounds has been studied in micellar media in order to observe the effect on regioselectivity and conversion of the reaction. The addition of surfactant causes a change in the chemical shifts of the aromatic proton resonance of phenol which proves the orientation of the aromatic compound on the micellar surface. However, increase in ionic strength of the reaction media affects the selectivity of reaction by disturbing this spatial orientation of the aromatic compound in the micelle. Selectivity towards particular isomers is dependent on the concentration of the surfactant. In bromination of chlorobenzene (deactivated aromatic compound) enhancement in selectivity and conversion towards the para isomer has been observed.
Iodination of anilines and phenols with 18-crown-6 supported ICl 2-
Mbatia, Hannah W.,Ulloa, Olbelina A.,Kennedy, Daniel P.,Incarvito, Christopher D.,Burdette, Shawn C.
experimental part, p. 2987 - 2991 (2011/06/16)
A highly crystalline iodinating reagent, {[K·18-C-6]ICl 2}n, was synthesized in high yield (93%). The trihalide is supported by an 18-crown-6 macrocycle and forms a coordination polymer in the solid state. This reagent iodinates anilines and phenols efficiently under mild conditions. Controlled mono-iodination with anilines was easily achieved while poly-iodination was observed with phenols.