6070-75-3 Usage
Description
3-Methylglutamic Acid is a non-proteinogenic amino acid derivative of glutamic acid, featuring an additional methyl group attached to the third carbon atom of the glutamate molecule. It plays a significant role as a positive allosteric modulator for the metabotropic glutamate receptor subtype 4 (mGlu4), which is involved in the regulation of neurotransmitter release in the brain. This modulation may have potential implications for the treatment of neurological disorders.
Uses
Used in Pharmaceutical Industry:
3-Methylglutamic Acid is used as a therapeutic agent for the potential treatment of neurological disorders due to its action as a positive allosteric modulator for the mGlu4 receptor. Its modulation of neurotransmitter release in the brain may contribute to managing various neurological conditions.
Used in Neuroscientific Research:
3-Methylglutamic Acid is utilized as a research tool in neuroscientific studies to investigate the role of mGlu4 receptors in neurotransmission and their potential involvement in neurological disorders. This helps in understanding the receptor's function and identifying new therapeutic targets for related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 6070-75-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,7 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6070-75:
(6*6)+(5*0)+(4*7)+(3*0)+(2*7)+(1*5)=83
83 % 10 = 3
So 6070-75-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO4.ClH/c1-3(2-4(8)9)5(7)6(10)11;/h3,5H,2,7H2,1H3,(H,8,9)(H,10,11);1H/t3-,5+;/m0./s1
6070-75-3Relevant articles and documents
threo-Selective Michael Addition of N,N-Dibenzylglycinate and Alaninate Enolates to α,β-Unsaturated Esters. A Concise and Stereoselective Synthesis of (+/-)-CCG-II
Yamaguchi, Masahiko,Torisu, Kazuhiko,Minami, Toru
, p. 377 - 380 (2007/10/02)
Lithium enolates of N,N-dibenzylglycinate and alaninate added to β-substituted α,β-unsaturated esters, and threo-adducts were obtained in high stereoselectivities.The reaction was employed in a concise and stereoselective synthesis of (+/-)-CCG-II.
