608-25-3Relevant articles and documents
Method for simultaneously preparing 2-methyl resorcinol and 4-methyl resorcinol
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Paragraph 0034-0066, (2022/01/10)
The invention provides a method for simultaneously preparing 2-methyl resorcinol and 4-methyl resorcinol, and belongs to the technical field of organic synthesis. The method comprises the following steps: resorcinol and methanol are subjected to an alkylation reaction through a metal phosphate stationary phase catalyst, and 2-methyl resorcinol and 4-methyl resorcinol are obtained. According to the method, the metal phosphate is used as the catalyst, the 2-methyl resorcinol and the 4-methyl resorcinol can be obtained at the same time by controlling the type of the catalyst, the resorcinol conversion rate is high, the joint selectivity of the 2-methyl resorcinol and the 4-methyl resorcinol can reach 60% at most, the selectivity of other products, namely intermediate hydroxyanisole is about 30%, the selectivity of m-xylylene dimethyl ether is about 5%, and the obtained products are all important intermediates for fine chemical engineering, organic chemistry and drug synthesis and are high in economic benefit. Meanwhile, methanol is used as a methylation reagent, so that the method is environment-friendly and low in price, and the production cost is reduced.
Method for synthesizing M-hydroxyanisole
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Paragraph 0032-0033; 0052-0053; 0056-0057; 0060-0063, (2021/11/03)
The invention provides a method for synthesizing M-hydroxyanisole. Belong to organic synthesis technical field. The synthesis method comprises the following steps: a vapor phase mixture of resorcinol and methanol is subjected to alkylation reaction through a metal phosphate - alumina fixed phase catalyst to obtain m-hydroxyanisole. The method adopts the gas-solid phase alkylation method to synthesize the M-hydroxyanisole without separating the reaction product from the catalyst, has the characteristic of continuous reaction, and can realize continuous production in the industrial production process. The method utilizes the acid-base catalytic activity center on the surface of the stationary phase catalyst to catalyze the reaction of resorcinol and methanol, and has high resorcinol conversion rate. The method has the advantage of high selectivity of m-hydroxyanisole. Methanol is used as a methylation reagent, and the method is environmentally friendly, low in cost and high in economic benefit.
Method for synthesizing 2,6-dihydroxytoluene by using waste acid
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, (2021/08/07)
The invention discloses a method for synthesizing 2,6-dihydroxytoluene by using waste acid mechanically. According to the method, 3-chloro-2-methylaniline is taken as a raw material, an intermediate 3-chloro-2-methylphenol is synthesized through diazotization and hydrolysis, the reaction is optimized in the alkali fusion, acidification and refining processes, the mechanical application of waste acid and a solvent in the reaction and the optimization of a refining scheme are emphatically optimized, the yield is effectively improved, three wastes are reduced, and 2,6-dihydroxytoluene is synthesized. The method provided by the invention greatly reduces the generation of acidic wastewater, better meets the requirement of environmental protection, and effectively increases the yield of the product, and the quality of the product reaches 99.0-99.5%.