60835-73-6

Basic information

• Product Name: 4'-FORMYLBENZO-15-CROWN 5-ETHER
• Synonyms: 2,3,5,6,8,9,11,12-Octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin-15-carbaldehyde;3,4-(Oxybisethylenebisoxybisethylenebisoxy)benzaldehyde;3,4-[Oxybis(ethyleneoxyethyleneoxy)]benzaldehyde;6,7,9,10,12,13,15,16-Octahydro-5,8,11,14,17-pentaoxa-5H-benzocyclopentadecene-2-carbaldehyde;Nsc288923;4'-FORMYLBENZO-15-CROWN-5;4'-FORMYLBENZO-15-CROWN 5-ETHER;2,3-(4-FORMYLBENZO)-1,4,7,10,13-PENTAOXACYCLOPENTADEC-2-ENE
• CAS NO: 60835-73-6
• Molecular Formula: C₁₅H₂₀O₆
• Molecular Weight: 296.32
• Product Categories: Chelation/Complexation Compounds;Aldehydes;Building Blocks;C13-C60;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Synthetic Reagents;Crown Ethers;Functional Materials;Macrocycles for Host-Guest Chemistry;Chelation/Complexation Compounds;Crown Ethers;Synthetic Reagents
• Mol File: 60835-73-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 78-81 °C(lit.)
• Boiling Point: 458.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.127±0.06 g/cm3(Predicted)
• BRN: 1627198
• CAS DataBase Reference: 4'-FORMYLBENZO-15-CROWN 5-ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-FORMYLBENZO-15-CROWN 5-ETHER(60835-73-6)
• EPA Substance Registry System: 4'-FORMYLBENZO-15-CROWN 5-ETHER(60835-73-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 60835-73-6(Hazardous Substances Data)

Usage

General Description

4'-Formylbenzo-15-crown-5-ether is a complex chemical compound that belongs to the crown ether family. It consists of a 15-membered macrocyclic ring with a formyl group attached to the 4' position of the benzene ring. 4'-FORMYLBENZO-15-CROWN 5-ETHER is known for its ability to selectively bind and transport specific cations, particularly alkali metal ions, due to its crown ether structure. It has been widely studied for its potential applications in ion recognition, ion-selective membrane systems, and other fields of supramolecular chemistry. Its unique structure and properties make it a promising candidate for various molecular recognition and ion sensing applications.

Upstream product

• 74357-36-1 4'-(2-phenyl-1,2-dioxoethyl)benzo-15-crown-5 
• 60835-72-5 4'-bromobenzo-15-crown-5-ether 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 71907-65-8 5-(6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-ylmethylene)-1-phenyl-pyrimidine-2,4,6-trione 
• 124384-07-2 5-(2,3-benzo-1,4,7,10,13-pentaoxa-2-cyclopentadecen-4'-yl)-10,15,20-tri(4-pyridyl)porphyrin 
• 124362-39-6 5,15-di(2,3-benzo-1,4,7,10,13-pentaoxa-2-cyclopentadecen-4'-yl)-10,20-di(4-pyridyl)porphyrin 
• 124362-40-9 5,10-di(2,3-benzo-1,4,7,10,13-pentaoxa-2-cyclopentadecen-4'-yl)-15,20-di(4-pyridyl)porphyrin 
• 16834-13-2 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine 
• 124362-41-0 5-(4-pyridyl)-10,15,20-tri(2,3-benzo-1,4,7,10,13-pentaoxa-2-cyclopentadecen-4'-yl)porphyrin 
• 127719-29-3 C₃₃H₃₂N₂O₇S₂ 
• 127719-34-0 C₃₅H₃₆N₂O₇S₂ 
• 127719-32-8 C₃₃H₃₀Cl₂N₂O₇S₂ 
• 127719-31-7 C₃₃H₃₀Br₂N₂O₇S₂ 
• 127740-01-6 C₃₅H₃₆N₂O₉S₂ 
• 127719-35-1 C₃₇H₄₀N₂O₇S₂ 
• 144339-13-9 N-(2,4-Dinitro-6-trifluoromethyl-phenyl)-N'-[1-(6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-yl)-meth-(E)-ylidene]-hydrazine 
• 127719-36-2 C₃₉H₄₄N₂O₇S₂ 

Relevant articles and documents

Synthesis of formyl derivatives of benzocrown ethers containing N, S, and O heteroatoms in the macrocycle

A method for the synthesis of 4'-bromobenzodithia-15(18)-crown-5(6) and 4'-bromobenzodiaza-15(18)-crown-5(6) by condensation of 3,4-di(2'-haloethoxy)bromobenzene with polyoxaalkanes containing terminal SH or NHMe groups was suggested.The method for the synthesis of formyl derivatives of benzocrowns containing N, S, and O heteroatoms in the macrocycle based on the metallation of appropriate bromo derivatives with BunLi followed by treatment of the resulting organolithium intermediates with DMF was developed.Oximes and semicarbazones of benzaldehydes containing a crown ether fragment were obtained, and their transformation into the original aldehydes by treatment with KNO2 in an acid medium was studied. - Key words: 4'-bromobenzocrowns, synthesis, metallation; 4'-formylbenzocrown ethers; semicarbazones and oximes of 4'-formylbenzocrown ethers.