609-54-1

Basic information

• Product Name: 2,5-Dimethylbenzenesulfonic acid dihydrate
• Synonyms: P-TOLUENE-O-SULFONIC ACID;P-XYLENE-2-SULFONIC ACID;P-XYLENESULFONIC ACID;2,5-dimethyl-benzenesulfonicaci;2,5-DIMETHYLBENZENESULFONIC ACID;p-xylene-2-sulphonic acid;XYLENOLSULFONIC ACID 65%;2,5-Dimethylbenzenesulfonic acid dihydrate
• CAS NO: 609-54-1
• Molecular Formula: C₈H₁₀O₃S
• Molecular Weight: 186.23
• EINECS: 210-193-5
• Product Categories: Industrial/Fine Chemicals;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonic/Sulfinic Acids;Sulfur Compounds
• Mol File: 609-54-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 86°C
• Boiling Point: 290.72°C (rough estimate)
• Flash Point: 275.2°C
• Appearance: /
• Density: 1.3286 (rough estimate)
• Vapor Pressure: 4E-12mmHg at 25°C
• Refractive Index: 1.5081 (estimate)
• Storage Temp.: 2-8°C
• PKA: -0.47±0.30(Predicted)
• Water Solubility: Soluble in water
• Sensitive: Hygroscopic
• CAS DataBase Reference: 2,5-Dimethylbenzenesulfonic acid dihydrate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethylbenzenesulfonic acid dihydrate(609-54-1)
• EPA Substance Registry System: 2,5-Dimethylbenzenesulfonic acid dihydrate(609-54-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 609-54-1(Hazardous Substances Data)

Usage

Uses

Reagent for serum cholesterol determination.

InChI:InChI=1/C8H10O3S.2H2O/c1-6-3-4-7(2)8(5-6)12(9,10)11;;/h3-5H,1-2H3,(H,9,10,11);2*1H2

Upstream product

• 106-42-3 para-xylene 
• 45867-06-9 2,5-dimethyl-benzenesulfinic acid 

Downstream Products

• 107100-45-8 2,5-dimethyl-benzenesulfonic acid-(4-bromo-phenacyl ester) 
• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 553-94-6 4-bromo-m-xylene 
• 1074-24-4 2,5-dibromo-p-xylene 
• 1124-05-6 1,4-dichloro-2,5-dimethylbenzene 
• 80509-27-9 3,6-dimethyl-2-nitro-benzenesulfonic acid 
• 19040-62-1 2,5-dimethylbenzenesulfonyl chloride 
• 62454-72-2 4-methyl-3-sulfobenzoic acid 
• 50619-01-7 3-amino-2,5-dimethyl-benzenesulfonic acid 
• 92147-52-9 2-(2,5-dimethyl-benzenesulfonyl)-isothiazolidine 1,1-dioxide 
• 80524-37-4 2,5-Dimethyl-benzenesulfonic acid 2-oxo-pentyl ester 
• 106-42-3 para-xylene 
• 19544-68-4 2,5-dimethyl-4-nitro-benzenesulfonic acid 
• 80509-28-0 2,5-dimethyl-3-nitro-benzenesulfonic acid 

Relevant articles and documents

Cornforth and Corey-Suggs reagents as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 under solvent free and microwave conditions

Cornforth and Corey-Suggs reagents Pyridinium Dichromate (PDC) and Pyridinium Chlorochromate (PCC) were explored as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 in aqueous acetonitrile medium at room temperature within 1–4 h, while microwave assisted reactions took place within 1–4 min under solvent-free conditions. These observations indicate significant rate accelerations in microwave assisted reactions. which were explained due to the bulk activation of molecules induced by insitu generated high temperatures and pressures when microwaves are transmitted through reaction medium.

A novel method for sulfonation of aromatic rings with silica sulfuric acid

Direct and chemoselective sulfonation of aromatic compounds with silica sulfuric acid in 1,2-dichloeoethane or under solvent-free conditions.