613-36-5

Basic information

• Product Name: 1-CYCLOHEXYL-4-METHOXY-BENZENE
• Synonyms: 1-CYCLOHEXYL-4-METHOXY-BENZENE;LABOTEST-BB LT00239188;1-Methoxy-4-cyclohexylbenzene;3-(4-Methoxyphenyl)cyclohexane;4-Cyclohexyl-1-methoxybenzene;4-Cyclohexylanisole;4-Methoxy-1-cyclohexylbenzene;p-Cyclohexylanisole
• CAS NO: 613-36-5
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 613-36-5.mol
• Article Data: 87

Chemical Properties

• Boiling Point: 286.8°C at 760 mmHg
• Flash Point: 132.1°C
• Appearance: /
• Density: 0.977g/cm³
• Vapor Pressure: 0.00447mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: 1-CYCLOHEXYL-4-METHOXY-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYCLOHEXYL-4-METHOXY-BENZENE(613-36-5)
• EPA Substance Registry System: 1-CYCLOHEXYL-4-METHOXY-BENZENE(613-36-5)

Safety Data

• Hazardous Substances Data: 613-36-5(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Solubility

Insoluble in water, soluble in organic solvents

Usage

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Application

Fragrance and flavoring agent in perfumes and food products

Potential applications

Building block for organic synthesis and creation of complex molecules

Safety

Potential health hazards, should be handled with caution and proper safety protocols

InChI:InChI=1/C13H18O/c1-14-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h7-11H,2-6H2,1H3

Upstream product

• 37087-68-6 2-(4-methoxyphenyl)cyclohexanone 
• 286-20-4 cyclohexane-1,2-epoxide 
• 100-66-3 methoxybenzene 
• 110-83-8 cyclohexene 
• 108-93-0 cyclohexanol 
• 613-37-6 4-methoxylbiphenyl 
• 108-94-1 cyclohexanone 
• 933-40-4 cycloxexanone dimethyl ketal 
• 16156-56-2 cyclohexyl mesylate 
• 7637-07-2 boron trifluoride 
• 7446-70-0 aluminium trichloride 
• 7664-93-9 sulfuric acid 
• 123-91-1 1,4-dioxane 
• 64-17-5 ethanol 

Downstream Products

• 412033-83-1 4-(5-cyclohexyl-2-methoxy-phenyl)-4-oxo-butyric acid 
• 1204-84-8 (4-cyclohexyl-cyclohexa-1,4-dienyl)-methyl ether 
• 1706-64-5 4-cyclohexyl-2-nitro-anisole 
• 1131-60-8 p-cyclohexylphenol 
• 1504-96-7 p-cyclohexylphenetole 

Relevant articles and documents

Mild and Selective Rhodium-Catalyzed Transfer Hydrogenation of Functionalized Arenes

Diboron-mediated rhodium-catalyzed transfer hydrogenation of functionalized arenes is reported. In addition to good functional group tolerance, the reaction features operational simplicity and controllable chemoselectivity. The general applicability of this procedure is demonstrated by the selective hydrogenation of a range of arenes, including functionalized benzenes, biphenyls, and polyaromatics.

Dilithium Amides as a Modular Bis-Anionic Ligand Platform for Iron-Catalyzed Cross-Coupling

Dilithium amides have been developed as a bespoke and general ligand for iron-catalyzed Kumada-Tamao-Corriu cross-coupling reactions, their design taking inspiration from previous mechanistic and structural studies. They allow for the cross-coupling of alkyl Grignard reagents with sp2-hybridized electrophiles as well as aryl Grignard reagents with sp3-hybridized electrophiles. This represents a rare example of a single iron-catalyzed system effective across diverse coupling reactions without significant modification of the catalytic protocol, as well as remaining operationally simple.

Dealkenylative Ni-Catalyzed Cross-Coupling Enabled by Tetrazine and Photoexcitation

A new and general method to functionalize the C(sp3)-C(sp2) bond of alkyl and alkene linkages has been developed, leading to the dealkenylative generation of carbon-centered radicals that can be intercepted to undergo Ni-catalyzed C(sp3)-C(sp2) cross-coupling. This one-pot protocol leverages the easily procured alkene feedstocks for organic synthesis with excellent functional group compatibility without the need for a photoredox catalyst.