613-85-4

Basic information

• Product Name: (2,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE
• Synonyms: (2,5-dimethylphenyl)hydrazine;Albb-006078
• CAS NO: 613-85-4
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.2
• Mol File: 613-85-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE(613-85-4)
• EPA Substance Registry System: (2,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE(613-85-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 613-85-4(Hazardous Substances Data)

Usage

General Description

(2,5-dimethylphenyl)hydrazine hydrochloride is a chemical compound that is typically used in pharmaceutical research and synthesis. It is a hydrazine derivative with a chlorine ion, and is commonly used in the preparation of various organic compounds and pharmaceutical products. (2,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE is known for its ability to react with other chemicals to form new compounds with medicinal properties. It is important to handle this chemical with care, as hydrazines are known to be toxic and potentially hazardous to human health. Additionally, proper safety precautions should be taken when working with and storing (2,5-dimethylphenyl)hydrazine hydrochloride to prevent potential harm.

Upstream product

• 95-78-3 2,5-Dimethylaniline 
• 88578-19-2 2,5-dimethyl-benzenediazonium; chloride 
• 2493-58-5 2,5-dimethylphenyl tosylate 
• 89-58-7 mononitro-p-xylene 

Downstream Products

• 134724-60-0 1-(2,5-dimethyl-phenyl)-pyrazolidin-3-one 
• 896736-80-4 N-(2,5-dimethyl-phenyl)-N'-(2,4-dinitro-phenyl)-hydrazine 
• 133131-71-2 2-(2,5-dimethyl-phenylhydrazono)-propionic acid ethyl ester 
• 6304-60-5 formic acid-[N'-(2,5-dimethyl-phenyl)-hydrazide] 
• 35774-21-1 2,5-dimethylphenyl azide 
• 113575-79-4 C₁₃H₁₉N₃S 
• 79005-96-2 1-(2,5-Dimethyl-phenylamino)-3-phenyl-1,3-dihydro-indol-2-one 
• 1375275-51-6 (S)-N-(benzo[d][1,3]dioxol-5-yl)-2-(2-(1-ethyl-2,4,7-trimethyl-1H-indol-3-yl)acetamido)-N-methyl-3-phenylpropanamide 
• 1432062-35-5 ethyl 6-amino-5-cyano-1-(2,5-dimethylphenyl)-4-(2-ethoxy-2-oxoethyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-4-carboxylate 
• 861086-41-1 acetic acid-[N'-(2,5-dimethyl-phenyl)-hydrazide] 

Relevant articles and documents

Diversification of edaravone via palladium-catalyzed hydrazine cross-coupling: Applications against protein misfolding and oligomerization of beta-amyloid

N-Aryl derivatives of edaravone were identified as potentially effective small molecule inhibitors of tau and beta-amyloid aggregation in the context of developing disease-modifying therapeutics for Alzheimer's disease (AD). Palladium-catalyzed hydrazine monoarylation protocols were then employed as an expedient means of preparing a focused library of 21 edaravone derivatives featuring varied N-aryl substitution, thereby enabling structure-activity relationship (SAR) studies. On the basis of data obtained from two functional biochemical assays examining the effect of edaravone derivatives on both fibril and oligomer formation, it was determined that derivatives featuring an N-biaryl motif were four-fold more potent than edaravone.

Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities

The invention relates to chromogenic compounds and the use thereof for the determination of enzymes of the family of carboxypeptidases N and carboxypeptidases U. The above is more specifically a compound of formula (I) in which A=(1), (2), (3), (4) or (5). R1. R2=H. —CH3, —CH(CH3)2, —OCH3, —Cl.—CF3,—OCF3,—SCH3, R3=an amino acid group which may be hydrolysed by a carboxypeptidase A and R4=a basic amino acid group.