61389-30-8

Basic information

• Product Name: OXONOL V
• Synonyms: 1,5-BIS(3-PHENYL-5-OXOISOXAZOL-4-YL)PENTAMETHINE OXONOL;4-[5-(5-HYDROXY-3-PHENYL-4-ISOXAZOLYL)-2,4-PENTADIENYLIDENE]-3-PHENYL-5(4H)-ISOXAZOLONE;BIS-(3-PHENYL-5-OXOISOXAZOL-4-YL)PENTAMETHINE OXONOL;OXONOL V;4-(5-(5-HYDROXY-3-PHENYL-4-ISOXAZOLYL)-&;OXONOL V, FOR FLUORESCENCE;4-(5-(5-HYDROXY-3-PHENYL-4-ISOXAZOLYL)-2,4-PENTADIENYLIDENE)-PH -ISOXAZOLONE;4-[5-(5-hydroxy-3-phenyl-4-isoxazolyl)-2,4-pentadienyliden
• CAS NO: 61389-30-8
• Molecular Formula: C23H16N2O4
• Molecular Weight: 384.38
• Product Categories: Oxonol;Isoxazole
• Mol File: 61389-30-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 170 °C (dec.)(lit.)
• Boiling Point: 634.1 °C at 760 mmHg
• Flash Point: 337.3 °C
• Appearance: Dark green/powder
• Density: 1.25g/cm³
• Vapor Pressure: 1.12E-09mmHg at 25°C
• Refractive Index: 1.631
• Storage Temp.: −20°C
• Solubility: Soluble in ethanol, methanol, dimethyl sulfoxide
• PKA: 5.51±0.50(Predicted)
• CAS DataBase Reference: OXONOL V(CAS DataBase Reference)
• NIST Chemistry Reference: OXONOL V(61389-30-8)
• EPA Substance Registry System: OXONOL V(61389-30-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 61389-30-8(Hazardous Substances Data)

Usage

Description

OXONOL V, also known as DiBAC4(3), is a fluorescent dye that is used as a potential sensitive probe. It is a lipophilic, cationic carbocyanine dye that can be used to measure changes in membrane potential.

Uses

Used in Biomedical Research:
OXONOL V is used as a fluorescent probe for determining the plasma membrane potential of neutrophils generated by the Na+ pump. It allows researchers to study the changes in membrane potential, which can provide insights into various cellular processes and functions.
Used in Cell Biology:
OXONOL V is used as a membrane potential-sensitive dye in cell biology research. It can be used to monitor changes in membrane potential in various cell types, including neurons, muscle cells, and immune cells. This can help researchers understand the mechanisms of ion transport and membrane potential regulation in different cell types.
Used in Drug Screening:
OXONOL V can be used as a tool in drug screening to identify compounds that affect membrane potential. By monitoring the changes in fluorescence upon drug treatment, researchers can evaluate the potential effects of drugs on membrane potential and ion transport.
Used in Environmental Monitoring:
OXONOL V can be used as a sensitive probe for detecting changes in environmental conditions, such as pH and temperature, that may affect membrane potential. This can be useful for monitoring the health of aquatic ecosystems and assessing the impact of environmental stressors on aquatic organisms.

InChI:InChI=1/C23H16N2O4/c26-22-18(20(24-28-22)16-10-4-1-5-11-16)14-8-3-9-15-19-21(25-29-23(19)27)17-12-6-2-7-13-17/h1-15,24H/b9-3+,14-8+,19-15-