615-82-7

Basic information

• Product Name: DL-LEUCYL-GLYCINE
• Synonyms: [(2-Amino-4-methylpentanoyl)amino]acetic acid;Glycine, N-DL-leucyl-;DL-LEU-GLY;DL-LEUCYL-GLYCINE;H-DL-LEU-GLY-OH;N-DL-leucylglycine;rac-N-[(R*)-2-Isobutylglycyl]glycine;2-[(2-amino-4-methylpentanoyl)amino]acetic acid
• CAS NO: 615-82-7
• Molecular Formula: C₈H₁₆N₂O₃
• Molecular Weight: 188.22
• EINECS: 210-449-6
• Product Categories: Amino Acid Derivatives;Biochemistry;Oligopeptides;Peptide Synthesis
• Mol File: 615-82-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 323.23°C (rough estimate)
• Flash Point: 202 °C
• Appearance: /
• Density: 1.1793 (rough estimate)
• Vapor Pressure: 6.97E-08mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Storage Temp.: −20°C
• PKA: pK1:3.25(＋1);pK2:8.28(0) (25°C)
• CAS DataBase Reference: DL-LEUCYL-GLYCINE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-LEUCYL-GLYCINE(615-82-7)
• EPA Substance Registry System: DL-LEUCYL-GLYCINE(615-82-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 615-82-7(Hazardous Substances Data)

Usage

General Description

DL-Leucyl-Glycine, also known as Leucylglycine, is a dipeptide composed of the amino acids leucine and glycine. It is a white crystalline powder with a molecular formula of C8H16N2O3 and a molecular weight of 188.22 g/mol. DL-Leucyl-Glycine is commonly used as a biochemical reagent and in the production of pharmaceuticals and research applications. It plays a role in protein synthesis and can act as a substrate for various enzymes involved in metabolism. Additionally, it has been studied for its potential therapeutic effects in conditions such as cancer and metabolic disorders. Overall, DL-Leucyl-Glycine is an important compound with diverse applications in the fields of biochemistry, pharmaceuticals, and medicine.

InChI:InChI=1/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

Upstream product

• 252351-90-9 N-benzyloxycarbonyl-leucyl-glycine 
• 4337-37-5 Leucyl-glycyl-glycin 
• 59685-29-9 glycyl=>leucyl=>glycine 
• 85864-65-9 [(S)-2-(2-{(S)-2-[2-((S)-2-Amino-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoylamino}-acetylamino)-3-methyl-butyrylamino]-acetic acid 
• 10034-85-2 hydrogen iodide 
• 2018-66-8 N-carbobenzyloxy leucine 
• 2778-33-8 N-(N-benzyloxycarbonyl-DL-leucyl)-glycine ethyl ester 

Downstream Products

• 53375-57-8 protected dipeptide 
• 16369-17-8 2-amino-4-methylpentan-1-ol 
• 61-90-5 L-leucine 
• 997-05-7 D-leucylglycine 
• 128395-64-2 N-(N-bromoacetyl-leucyl)-glycine 
• 92325-87-6 N-[N-(2.4-dinitro-phenyl)-DL-leucyl]-glycine 
• 121975-25-5 N-leucyl-glycine benzyl ester 
• 56-40-6 glycine 
• 328-39-2 LEUCINE 
• 625-28-5 Isovaleronitrile 
• 25117-57-1 2-bromo-3-methylbutyronitrile 
• 1643-39-6 2-amino-4,6-di-tertbutylphenol 
• 82267-71-8 alanyl=>leucyl=>-glycine 
• 503-74-2 3-methylbutyric acid 

Relevant articles and documents

Peptide Synthesis Using the Pyrrole Ring as an Amino Protecting Group

The utility of a pyrrole ring as an amino protecting group for amino acids in peptide synthesis has been studied.The N-termini of various amino acids (1) were protected with a pyrrole ring by treatment with 2,5-dimethoxytetrahydrofuran (10) to give 2-substituted 2-(1-pyrrolyl)acetic acids (11).The peptide bond between (11) and amino acid methyl ester (2) was formed using N,N'-dicyclohexylcarbodiimide, and the pyrrole ring was cleaved by ozonolysis and hydrolysis without the cleavage of a peptide bond to give the corresponding dipeptide compounds (26) in good yields.