615-84-9

Basic information

• Product Name: N,N'-DIETHYLOXAMIDE
• Synonyms: N,N'-DIETHYLOXAMIDE;SALOR-INT L158526-1EA;TIMTEC-BB SBB007900;Ethanediamide, N,N'-diethyl-;N,N'-Diethyloxalamide;Oxamide, N,N'-diethyl-;N,N'-Diethyloxamide,98%;sym-Diethyl oxamide
• CAS NO: 615-84-9
• Molecular Formula: C₆H₁₂N₂O₂
• Molecular Weight: 144.17
• EINECS: 210-451-7
• Mol File: 615-84-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 174-175°C
• Boiling Point: 262.78°C (rough estimate)
• Appearance: /
• Density: 1.1690
• Refractive Index: 1.4500 (estimate)
• CAS DataBase Reference: N,N'-DIETHYLOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIETHYLOXAMIDE(615-84-9)
• EPA Substance Registry System: N,N'-DIETHYLOXAMIDE(615-84-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 615-84-9(Hazardous Substances Data)

Usage

General Description

N,N'-Diethyl Oxamide is an organic compound prominently used in chemical industries. It belongs to the family of oxamides, which are organic compounds containing an oxamic acid amide functional group. This chemical is generally used as an intermediate in the synthesis of various chemical products. N,N'-Diethyl Oxamide is a derivative of oxamide and is characterized by its two ethyl groups. Its chemical formulation is C6H14N2O2, featuring oxygen, hydrogen, carbon, and nitrogen molecules. It is primarily used in the laboratory setting and in industrial production due to its specialized properties. It's crucial to handle this substance with care as its potential health and environmental impacts are yet to be fully understood.

Upstream product

• 553-90-2 Dimethyl oxalate 
• 75-04-7 ethylamine 
• 82700-97-8 perfluoro-<(1-ethyl-1-methylpropyl)(1-methylpropyl)>ethanolide 
• 201230-82-2 carbon monoxide 
• 16475-50-6 N,N'-diethyldithiooxamide 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 2302-28-5 5-chloro-1-ethyl-2-methyl-4-nitro-1H-imidazole 
• 4897-22-7 5-chloro-1-ethyl-2-methyl-1H-imidazole 

Relevant articles and documents

Theoretical, structural, vibrational, NMR, and thermal evidence of the inter- versus intramolecular hydrogen bonding in oxamides and thiooxamides

This contribution describes the study of hydrogen bonding in secondary oxamides, monothiooxamides, and dithiooxamides by ab initio calculations, X-ray diffractions, NMR spectra, thermal analysis, and variable-temperature infrared and Raman spectroscopy. The results can all be interpreted as a function of the change in the strength and the nature of the hydrogen bonding by substituting oxygen for sulfur in the series CH3-HNCOCONHCH3, CH 3HNCSCONHCH3, CH3HNCSCSNHCH3 and by changing the steric influence of the alkyl group in a series of oxamides (RHNCOCNHR; R = CH3, C2H5, iC3H 7, tC49).

Oxidative coupling of amines and carbon monoxide catalyzed by palladium complexes. Mono- and double carbonylation reactions promoted by iodine compounds.

Iodine is an effective promoter for the carbonylation of primary and secondary amines to ureas using palladium acetate as the catalyst and a base (e.g.K2CO3) in acetonitrile (3 h at 95 deg C and 2.7 atm).Oxamides are formed in excellent yields when secondary amines are carbonylated in the presence of iodide ion and oxygen, while primary amines give ureas as the principal product at 95 deg C, and oxamide at room temperature.