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6155-57-3

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6155-57-3 Usage

Description

Saccharin sodium dihydrate is the sodium dihydrate form of saccharin, which belongs to the family of aromatic homomonocyclic compounds. It is an artificial sweetener that is hundreds times as sweet as sucrose. It is mainly used as a food additive to sweeten many products such as drinks, candies, cookies, and medicine. Saccharin is relatively safe for human beings without providing food energy and any nutritional value. It is also safe for diabetes patients to consume.

Chemical Properties

dihydrate granular

Uses

Different sources of media describe the Uses of 6155-57-3 differently. You can refer to the following data:
1. Sweetener (non-nutritive).
2. Saccharin Sodium Salt Dihydrate is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.

References

https://en.wikipedia.org/wiki/Saccharin https://pubchem.ncbi.nlm.nih.gov/compound/saccharin#section=Top

Check Digit Verification of cas no

The CAS Registry Mumber 6155-57-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,5 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6155-57:
(6*6)+(5*1)+(4*5)+(3*5)+(2*5)+(1*7)=93
93 % 10 = 3
So 6155-57-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NO3S.Na.2H2O/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;;;/h1-4H,(H,8,9);;2*1H2/q;+1;;/p-1

6155-57-3 Well-known Company Product Price

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  • USP

  • (1607040)  Saccharinsodiumsaltdihydrate  United States Pharmacopeia (USP) Reference Standard

  • 6155-57-3

  • 1607040-100MG

  • 4,588.74CNY

  • Detail

6155-57-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name o-Benzoic Sulfimide Sodium Salt Dihydrate

1.2 Other means of identification

Product number -
Other names 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt, dihydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6155-57-3 SDS

6155-57-3Synthetic route

chloro(2,2':6',2''-terpyridine)platinum(II) chloride dihydrate

chloro(2,2':6',2''-terpyridine)platinum(II) chloride dihydrate

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

[(2,2':6',2''-terpyridine)chloroplatinum(II)]saccharinatedihydrate

[(2,2':6',2''-terpyridine)chloroplatinum(II)]saccharinatedihydrate

Conditions
ConditionsYield
In water silid metal complex dissolved in H2O at 60°C, treated with 1 equiv. of Na saccharinate dihydrate (2 equiv.), stirred at 60°C for 30 min; treated with EtOH, crystd. at room temp. for 3 d, elem. anal.;95%
[(2,2':6',2''-terpyridine)chloropalladium(II)]chloride dihydrate

[(2,2':6',2''-terpyridine)chloropalladium(II)]chloride dihydrate

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

[(2,2':6',2''-terpyridine)chloropalladium(II)]saccharinate dihydrate

[(2,2':6',2''-terpyridine)chloropalladium(II)]saccharinate dihydrate

Conditions
ConditionsYield
In water silid metal complex dissolved in H2O at 60°C, treated with 1 equiv. of Na saccharinate dihydrate (2 equiv.), stirred at 60°C for 30 min; treated with EtOH, crystd. at room temp. for 3 d, elem. anal.;95%
[(2,2':6',2''-terpyridine)chloropalladium(II)]chloride dihydrate

[(2,2':6',2''-terpyridine)chloropalladium(II)]chloride dihydrate

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[(2,2':6',2''-terpyridine)(saccharinate)palladium(II)]saccharinate - water (1/2.5)

[(2,2':6',2''-terpyridine)(saccharinate)palladium(II)]saccharinate - water (1/2.5)

Conditions
ConditionsYield
In water byproducts: AgCl; silid metal complex and solid AgNO3 (1:2) added to H2O, refluxed for 6 h, AgCl filtered (celite), concd., treated with Na saccharinate dihydrate(2 equiv.), stirred at 60°C for 30 min; mixed with EtOH, crystd. at room temp. for 2 d, elem. anal.;94.4%
2-Methylpyrazine
109-08-0

2-Methylpyrazine

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

Ag4(saccharinate)4(2-methylpyrazine)2(H2O)2

Ag4(saccharinate)4(2-methylpyrazine)2(H2O)2

Conditions
ConditionsYield
In water; acetonitrile solid Na(sac)*2H2O mixed with 1 equiv. of AgNO3 in H2O, pptd., dissolvedin CH3CN, treated with 1 equiv. of 2-methylpyrazine, stirred at room te mp. for 30 min; crystd. at room temp. in the dakness for 2 d, elem. anal.;94%
1-(2-aminoethyl)pyrrolidine
7154-73-6

1-(2-aminoethyl)pyrrolidine

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[Ag2(saccharate)2(N-(2-aminoethyl)pyrrolidine)2]

[Ag2(saccharate)2(N-(2-aminoethyl)pyrrolidine)2]

Conditions
ConditionsYield
In water; isopropyl alcohol a soln. of Na-saccharate in water was mixed with AgNO3 in water-2-propanol (1:3) with stirring, pyrrolidine-compound was added, the mixt. was stirred for 30 min at room temp.; allowed to stand in darkness at room temp. for 4 days; elem. anal.;93%
1H-imidazole
288-32-4

1H-imidazole

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[Ag(saccharinate)(imidazole)]*2H2O

[Ag(saccharinate)(imidazole)]*2H2O

Conditions
ConditionsYield
In water; isopropyl alcohol; acetonitrile aq. soln. of Na salt mixed with soln. of AgNO3 in H2O-i-PrOH (1:3) with stirring, ppt. dissolved in MeCN and N compd. added; evapd. slowly in dark at room temp. for 2 d; elem.anal;93%
S,S'-diphenylsulfimide monohydrate

S,S'-diphenylsulfimide monohydrate

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

Ag(saccharinato)(S,S-diphenylsulfimide)
930301-72-7

Ag(saccharinato)(S,S-diphenylsulfimide)

Conditions
ConditionsYield
In dichloromethane; water Na-salt mixed with soln. of AgNO3 in H2O, ppt. dissolved in CH2Cl2, ligand added, stirred for 30 min at room temp., allowed to stand in darknessat room temp. for 2 wk; elem. anal.;89%
sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

zinc(II) chloride
7646-85-7

zinc(II) chloride

tetraaquabis(saccharinato)zinc(II) dihydrate

tetraaquabis(saccharinato)zinc(II) dihydrate

Conditions
ConditionsYield
In water under N2, C7H4NO3SNa*2H2O in water was added to aq. soln. of ZnCl2 (molar ratio 2.25:1) with stirring; cooled to 0°C for 1 h, filtered, washed with cold water, dried;88%
trans dichlorobispyridine palladium (II)
14872-20-9, 15227-47-1, 14052-12-1

trans dichlorobispyridine palladium (II)

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

trans-Pd(1,1-dioxo-1,2-benzothiazol-3-one(1-))2(pyridine)2
1318240-28-6

trans-Pd(1,1-dioxo-1,2-benzothiazol-3-one(1-))2(pyridine)2

Conditions
ConditionsYield
With AgNO3 In water byproducts: AgCl; AgNO3 added to suspn. of Pd-complex in H2O, refluxed for 6 h, cooled to room temp., filtered, filtrate concd., Na-salt added, stirred at 60°C for 30 min, stirred at 60°C for 1 h, cooled to room temp.; filtered, recrystd. from DMSO; elem. anal.;88%
dipyridil[3,2-a:2',3'-c]phenazine
19535-47-8

dipyridil[3,2-a:2',3'-c]phenazine

copper(II) perchlorate hexahydrate

copper(II) perchlorate hexahydrate

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

[Cu(dipyrido[3,2-a:2′,3′-c]phenazine)2(saccharinate)]ClO4

[Cu(dipyrido[3,2-a:2′,3′-c]phenazine)2(saccharinate)]ClO4

Conditions
ConditionsYield
Stage #1: copper(II) perchlorate hexahydrate; sodium saccharinate dihydrate In methanol for 2h;
Stage #2: dipyridil[3,2-a:2',3'-c]phenazine In methanol at 60℃; for 4h;
88%
NH-pyrazole
288-13-1

NH-pyrazole

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[Ag(saccharinate)(pyrazole)(H2O)]n
917837-18-4

[Ag(saccharinate)(pyrazole)(H2O)]n

Conditions
ConditionsYield
In water; isopropyl alcohol; acetonitrile aq. soln. of Na salt mixed with soln. of AgNO3 in H2O-i-PrOH (1:3) with stirring, ppt. dissolved in MeCN and N compd. added; allowed to stand in dark at room temp. for 2 d; elem.anal;87%
2-(aminoethyl)pyridine
2706-56-1

2-(aminoethyl)pyridine

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

bis(2-(2-aminoethyl)pyridine)bis(saccharinato)disilver(I)
881006-83-3

bis(2-(2-aminoethyl)pyridine)bis(saccharinato)disilver(I)

Conditions
ConditionsYield
In water; isopropyl alcohol 1 equiv. of NA-salt was dissolved in H2O and added to AgNO3 in H2O-iPrOH=1:3, v/v, mixt., 1 equiv. of amine was added, stirring at room temp. for 30 min; mixt. was allowed to stand in darkness at room temp. for a week, elem. anal.;87%
1-piperidinoethanol
3040-44-6

1-piperidinoethanol

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

Ag(saccharinate)(N-(2-hydroxyethylethyl)piperidine)
1130870-85-7

Ag(saccharinate)(N-(2-hydroxyethylethyl)piperidine)

Conditions
ConditionsYield
In water; acetonitrile 1 equiv. of Na-salt in H2O to aq. AgNO3 soln., MeCN was added until dissoln., 1 equiv. of piperidine-compd. was added; mixt. was allowed to stand at room temp. in the darkness for 2 d, elem. anal.;87%
sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

2,5-bis(2-pyridyl)-3,4-diaza-2,4-hexadiene

2,5-bis(2-pyridyl)-3,4-diaza-2,4-hexadiene

[Ag2(saccharinato)2(1,2-bis[1-(pyridin-2-yl)ethylidene]hydrazine)]
1226813-78-0

[Ag2(saccharinato)2(1,2-bis[1-(pyridin-2-yl)ethylidene]hydrazine)]

Conditions
ConditionsYield
In further solvent(s) an aq. soln. of Na salt added to an aq. soln. of AgNO3, MeCN added, a MeOH soln. of ligand added dropwise, MeCN and i-PrOH added; crystd. in darkness at room temp. for 1 wk; elem. anal.;87%
2-[(dimethylamino)methyl]pyridin-3-ol
2168-13-0

2-[(dimethylamino)methyl]pyridin-3-ol

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[Ag(saccharate)(2-(dimethylaminomethyl)-3-hydroxypyridine)]
911321-27-2

[Ag(saccharate)(2-(dimethylaminomethyl)-3-hydroxypyridine)]

Conditions
ConditionsYield
In water; isopropyl alcohol a soln. of Na-saccharate in water was mixed with AgNO3 in water-2-propanol (1:3) with stirring, pyridine-compound was added, the mixt. was stirred for 30 min at room temp.; allowed to stand in darkness at room temp. for 4 days; elem. anal.;86%
1,4-bis(2-hydroxyethyl)piperazine
122-96-3

1,4-bis(2-hydroxyethyl)piperazine

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

[Ag(μ-saccharinato)(μ-N,N'-bis(2-hydroxyethyl)piperazine)](n)

[Ag(μ-saccharinato)(μ-N,N'-bis(2-hydroxyethyl)piperazine)](n)

Conditions
ConditionsYield
In water; isopropyl alcohol Na salt added to a soln. of AgNO3 in H2O and isopropanol, an aq. soln. of HOC2H4N(C2H4)2NC2H4OH added dropwise; crystd. for 4 d in the dark at room temp.; elem. anal.;86%
cis-dichloro(2,2'-dipyridylamine)palladium(II)
111693-13-1

cis-dichloro(2,2'-dipyridylamine)palladium(II)

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

cis-[Pd(2,2'-dipyridylamine)(saccharinate)2]*H2O
1245815-85-3

cis-[Pd(2,2'-dipyridylamine)(saccharinate)2]*H2O

Conditions
ConditionsYield
With AgNO3 In water byproducts: AgCl; AgNO3 (1 mmol) added to aq. suspn. of PdCl2(dpya) (0.5 mmol), refluxed for 6 h, cooled to room temp., AgCl filtered off, concd., Na(sac)*2H2O (1mmol) added, mixt. stirred at 60°C for 30 min; ppt. filtered off, recrystd. (H2O/DMF=1/1), elem. anal.;86%
(2-aminomethylpyridine)
3731-51-9

(2-aminomethylpyridine)

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

2-(aminomethyl)pyridinesaccharinatosilver(I)
881006-82-2

2-(aminomethyl)pyridinesaccharinatosilver(I)

Conditions
ConditionsYield
In water; isopropyl alcohol 1 equiv. of NA-salt was dissolved in H2O and added to AgNO3 in H2O-iPrOH=1:3, v/v, mixt., 1 equiv. of amine was added, stirring at room temp. for 30 min; mixt. was allowed to stand in darkness at room temp. for a week, elem. anal.;85%
sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

silver nitrate

silver nitrate

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

bis(N,N-dimethylethylenediamine)bis(saccharinato)disilver(I)

bis(N,N-dimethylethylenediamine)bis(saccharinato)disilver(I)

Conditions
ConditionsYield
In water; isopropyl alcohol Na salt added to soln. of AgNO3 in H2O-iPrOH (1:3), diamine added to suspn.; evapd. slowly at room temp., stand for 2 wk; elem. anal.;85%
di(pyridin-2-yl)amine
1202-34-2

di(pyridin-2-yl)amine

cis-dichloro(2,2'-dipyridylamine)palladium(II)
111693-13-1

cis-dichloro(2,2'-dipyridylamine)palladium(II)

water
7732-18-5

water

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

[Pd(2,2'-dipyridylamine)]2[saccharinate]2*2H2O

[Pd(2,2'-dipyridylamine)]2[saccharinate]2*2H2O

Conditions
ConditionsYield
In methanol; water aq. suspn. of PdCl2(dpya) (0.5 mmol) mixed with MeOH soln. of ligand (1 mmol), refluxed overnight, cooled to room temp., filtered, aq. soln. of Na(sac)*2H2O (1 mmol) added, mixt. stirred at 60°C for 2 h; concd., crystd. in 1 d, elem. anal.;85%
chloro(bis(2-pyridylmethyl)amine)palladium(II) chloride monohydrate
439120-09-9

chloro(bis(2-pyridylmethyl)amine)palladium(II) chloride monohydrate

sodium saccharinate dihydrate
6155-57-3

sodium saccharinate dihydrate

[Pd(bis(2-pyridylmethyl)amine)(saccharinato)](saccharinate)*2H2O

[Pd(bis(2-pyridylmethyl)amine)(saccharinato)](saccharinate)*2H2O

Conditions
ConditionsYield
With AgNO3 In water byproducts: AgCl; Pd-complex and solid AgNO3 were added to water and set to reflux for 6 h, AgCl was filtered, the filtrate was concd. and Na-saccharate was added, stirred at 60°C for 30 min; stand for 1 d; elem. anal.;85%

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