61558-12-1 Usage
Description
21-Dehydro BetaMethasone is a derivative of Betamethasone, a corticosteroid with potent anti-inflammatory properties. It is characterized by the absence of a hydrogen atom at the 21st position in its molecular structure, which distinguishes it from its parent compound. This modification may result in altered pharmacological properties, making it a subject of interest for further research and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
21-Dehydro BetaMethasone is used as an impurity in the production of Betamethasone, a corticosteroid with anti-inflammatory and immunosuppressive effects. It is utilized for the treatment of various conditions, including allergies, arthritis, asthma, and skin diseases. The presence of 21-Dehydro BetaMethasone in Betamethasone formulations may contribute to the overall therapeutic effects or require monitoring to ensure optimal safety and efficacy.
Additionally, due to its structural similarity to Betamethasone, 21-Dehydro BetaMethasone may have potential applications in the development of new corticosteroid drugs with improved properties, such as enhanced anti-inflammatory activity, reduced side effects, or increased stability.
Used in Research and Development:
21-Dehydro BetaMethasone can be used as a research compound for studying the structure-activity relationship of corticosteroids. Understanding how the absence of a hydrogen atom at the 21st position affects the pharmacological properties of Betamethasone can provide valuable insights into the design of novel corticosteroid drugs with improved therapeutic profiles.
Furthermore, 21-Dehydro BetaMethasone may serve as a starting material for the synthesis of other corticosteroid derivatives with potential applications in various therapeutic areas, such as inflammation, immunology, and dermatology.
Check Digit Verification of cas no
The CAS Registry Mumber 61558-12-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,5,5 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61558-12:
(7*6)+(6*1)+(5*5)+(4*5)+(3*8)+(2*1)+(1*2)=121
121 % 10 = 1
So 61558-12-1 is a valid CAS Registry Number.
61558-12-1Relevant articles and documents
Mechanism of base-catalyzed autooxidation of corticosteroids containing 20-keto-21-hydroxyl side chain
Li, Min,Chen, Bin,Monteiro, Stephanie,Rustum, Abu M.
scheme or table, p. 4575 - 4581 (2009/10/11)
Corticosteroids and related compounds containing the 20-keto-21-hydroxyl side chain such as betamethasone, betamethasone 9,11-epoxide, dexamethasone, and dexamethasone 9,11-epoxide have been found to undergo facile autooxidation on the 1,3-dihydroxyaceton
