61632-47-1

Basic information

• Product Name: 4-Imidazolidinone, 5-(1-methylethylidene)-3-phenyl-2-thioxo-
• CAS NO: 61632-47-1
• Molecular Formula: C12H12N2OS
• Molecular Weight: 232.306
• Mol File: 61632-47-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Imidazolidinone, 5-(1-methylethylidene)-3-phenyl-2-thioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Imidazolidinone, 5-(1-methylethylidene)-3-phenyl-2-thioxo-(61632-47-1)
• EPA Substance Registry System: 4-Imidazolidinone, 5-(1-methylethylidene)-3-phenyl-2-thioxo-(61632-47-1)

Safety Data

• Hazardous Substances Data: 61632-47-1(Hazardous Substances Data)

Upstream product

• 2010-15-3 3-phenyl-2-thioxoimidazolidin-4-one 
• 67-64-1 acetone 
• 103-85-5 monophenylthiourea 
• 2393-23-9 4-methoxy-benzylamine 
• 103774-42-1 5-isopropyl-3-phenylimidazolidine-2,4-dione 
• 22078-04-2 α,β-dehydrovaline ethylester 
• 103-72-0 phenyl isothiocyanate 
• 857964-62-6 2-anilino-5,5-dimethyl-4,5-dihydro-thiazole-4-carboxylic acid ethyl ester 

Relevant articles and documents

Unprecedented one-pot chemocontrolled entry to thioxoimidazolidinones and aminoimidazolones: Synthesis of kinase inhibitor Leucettamine B

A novel and highly chemoselective protocol for the construction of thioxoimidazolidinone and aminoimidazolone frameworks was explored, and the influence of the reaction conditions on product formation was studied to establish two distinct approaches for their selective formation. In this one-pot reaction, ambient temperature generally resulted in the formation of thioxoimidazolidinones, whereas microwave irradiation provided aminoimidazolones exclusively. An attempt to elucidate the observed chemoselectivity is described, and the products were confirmed by X-ray studies. One-pot synthesis toward Leucettamine B, a marine alkaloid, was achieved on the basis of this protocol.