61812-54-2

Basic information

• Product Name: Benzene, 1,1'-[oxybis(methylene)]bis[4-fluoro-
• CAS NO: 61812-54-2
• Molecular Formula: C14H12F2O
• Molecular Weight: 234.245
• Mol File: 61812-54-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[oxybis(methylene)]bis[4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[oxybis(methylene)]bis[4-fluoro-(61812-54-2)
• EPA Substance Registry System: Benzene, 1,1'-[oxybis(methylene)]bis[4-fluoro-(61812-54-2)

Safety Data

• Hazardous Substances Data: 61812-54-2(Hazardous Substances Data)

Upstream product

• 766-77-8 Dimethylphenylsilane 
• 459-57-4 4-fluorobenzaldehyde 
• 459-56-3 4-fluorobenzylic alcohol 
• 617-86-7 triethylsilane 
• 108-88-3 toluene 
• 459-46-1 4-Fluorobenzyl bromide 
• 93-55-0 1-phenyl-propan-1-one 
• 673-32-5 1-Phenylprop-1-yne 

Downstream Products

• 1581291-39-5 (E)-(4-fluorophenyl)(2-(phenyldiazenyl)phenyl)methanone 
• 1510826-85-3 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(4-fluorophenyl)methanone 
• 27064-94-4 4,4'-difluorobenzhydryl chloride 
• 352-32-9 p-fluorotoluene 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 69719-54-6 bis(4-fluorobenzyl) sulfide 

Relevant articles and documents

Bis(pertrifluoromethylcatecholato)silane: Extreme Lewis Acidity Broadens the Catalytic Portfolio of Silicon

Given its earth abundance, silicon is ideal for constructing Lewis acids of use in catalysis or materials science. Neutral silanes were limited to moderate Lewis acidity, until halogenated catecholato ligands provoked a significant boost. However, catalytic applications of bis(perhalocatecholato)silanes were suffering from very poor solubility and unknown deactivation pathways. In this work, the novel per(trifluoromethyl)catechol, H2catCF3, and adducts of its silicon complex Si(catCF3)2 (1) are described. According to the computed fluoride ion affinity, 1 ranks among the strongest neutral Lewis acids currently accessible in the condensed phase. The improved robustness and affinity of 1 enable deoxygenations of aldehydes, ketones, amides, or phosphine oxides, and a carbonyl-olefin metathesis. All those transformations have never been catalyzed by a neutral silane. Attempts to obtain donor-free 1 attest to the extreme Lewis acidity by stabilizing adducts with even the weakest donors, such as benzophenone or hexaethyl disiloxane.

Aryl Boronic Acid Catalysed Dehydrative Substitution of Benzylic Alcohols for C?O Bond Formation

A combination of pentafluorophenylboronic acid and oxalic acid catalyses the dehydrative substitution of benzylic alcohols with a second alcohol to form new C?O bonds. This method has been applied to the intermolecular substitution of benzylic alcohols to form symmetrical ethers, intramolecular cyclisations of diols to form aryl-substituted tetrahydrofuran and tetrahydropyran derivatives, and intermolecular crossed-etherification reactions between two different alcohols. Mechanistic control experiments have identified a potential catalytic intermediate formed between the aryl boronic acid and oxalic acid.

Efficient carbon-supported heterogeneous molybdenum-dioxo catalyst for chemoselective reductive carbonyl coupling

Reductive coupling of various carbonyl compounds to the corresponding symmetric ethers with dimethylphenylsilane is reported using a carbon-supported dioxo-molybdenum catalyst. The catalyst is air- and moisture-stable and can be easily separated from the reaction mixture for recycling. In addition, the catalyst is chemoselective, thus enabling the synthesis of functionalized ethers without requiring sacrificial ligands or protecting groups.