618386-06-4

Basic information

• Product Name: Diethyl ((5-((triisopropylsilyl) oxy) pyridin-2-yl)methyl) phosphonate
• Synonyms: Diethyl ((5-((triisopropylsilyl) oxy) pyridin-2-yl)methyl) phosphonate;(5-triisopropylsilanyloxypyridin-2-ylmethyl)phosphonic acid diethyl ester
• CAS NO: 618386-06-4
• Molecular Formula: C₁₉H₃₆NO₄PSi
• Molecular Weight: 402.560641
• Mol File: 618386-06-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Diethyl ((5-((triisopropylsilyl) oxy) pyridin-2-yl)methyl) phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl ((5-((triisopropylsilyl) oxy) pyridin-2-yl)methyl) phosphonate(618386-06-4)
• EPA Substance Registry System: Diethyl ((5-((triisopropylsilyl) oxy) pyridin-2-yl)methyl) phosphonate(618386-06-4)

Safety Data

• Hazardous Substances Data: 618386-06-4(Hazardous Substances Data)

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 1121-78-4 5-Hydroxy-2-methylpyridine 
• 1029100-88-6 2-methyl-5-triisopropylsilanyloxypyridine 
• 814-49-3 diethyl chlorophosphate 

Downstream Products

• 226912-84-1 (+)-(3R,3aS,4S,4aR,9aR)-decahydro-4-[(E)-2-[5-[3-(trifluoromethy)phenyl]l-2-pyridinyl]ethenyl]-3-methylnaphtho-[2,3-c]furan-1(3H)-one 

Relevant articles and documents

Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity

The discovery of an exceptionally potent series of thrombin receptor (PAR-1) antagonists based on the natural product himbacine is described. Optimization of this series has led to the discovery of 4 (SCH 530348), a potent, oral antiplatelet agent that is