6188-63-2

Basic information

• Product Name: 2.14. 1,1,1,3,3,3-HEXACHLORO-2-PROPANOL
• Synonyms: 2.14. 1,1,1,3,3,3-HEXACHLORO-2-PROPANOL;1,1,1,3,3,3-Hexachloro-2-propanol
• CAS NO: 6188-63-2
• Molecular Formula: C₃H₂Cl₆O
• Molecular Weight: 266.77
• Mol File: 6188-63-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 86-87 °C(Solv: hexane (110-54-3))
• Boiling Point: 244.4°C at 760 mmHg
• Flash Point: 101.6°C
• Appearance: /
• Density: 1.848g/cm³
• Vapor Pressure: 0.0051mmHg at 25°C
• Refractive Index: 1.557
• PKA: 10.30±0.20(Predicted)
• CAS DataBase Reference: 2.14. 1,1,1,3,3,3-HEXACHLORO-2-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2.14. 1,1,1,3,3,3-HEXACHLORO-2-PROPANOL(6188-63-2)
• EPA Substance Registry System: 2.14. 1,1,1,3,3,3-HEXACHLORO-2-PROPANOL(6188-63-2)

Safety Data

• Hazardous Substances Data: 6188-63-2(Hazardous Substances Data)

Usage

General Description

1,1,1,3,3,3-Hexachloro-2-propanol, also known as HCPO, is a synthetic chemical compound used in various industrial processes and products. It is a highly toxic and persistent contaminant, and exposure to it can have detrimental effects on human health and the environment. HCPO is classified as a possible human carcinogen and is known to cause skin and eye irritation upon contact. It is also considered to be harmful if inhaled or ingested, with potential effects on the liver, kidneys, and nervous system. Due to its persistence and toxicity, efforts are being made to reduce the production and use of HCPO, as well as to find effective methods for its removal and remediation from contaminated sites.

InChI:InChI=1/C3H2Cl6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

Upstream product

• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 
• 75-87-6 chloral 
• 114174-69-5 1-benzyl-2-methyl-1,4-dihydronicotinamide 
• 20557-70-4 1-Benzyl-6-methyl-1,4-dihydro-pyridine-3-carboxylic acid amide 
• 114174-70-8 1-Benzyl-2,6-dimethyl-1,4-dihydro-pyridine-3-carboxylic acid amide 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 302-17-0 chloral hydrate 
• 76-03-9 trichloroacetic acid 
• 121-44-8 triethylamine 
• 952-92-1 1-Benzyl-1,4-dihydronicotinamide 
• 17750-24-2 1-propyl-1,4-dihydronicotinamide 

Downstream Products

• 101166-89-6 1.1.1.3.3.3-Hexachlor-isopropyl-<3.5-dinitro-benzoat> 
• 28049-06-1 3-Phenylpropionsaeure-hexachlorisopropylester 
• 98994-99-1 1,1,1,3,3,3-Hexachlor-isopropyl-(4-nitro-benzoat) 

Relevant articles and documents

Steric and Electronic Effects of Methyl Substitutents at the 2- and 6-Positions on N-Benzyl-1,4-dihydronicotinamide

N-Benzyl-1,4-dihydronicotinamides having 2-methyl, 6-methyl and 2,6-dimethyl substituents were prepared and their reactivities toward an activated carbonyl compound (hexachloroacetone) were investigated.The reaction rates were especially enhanced for the

Macrocyclic Enzyme Model System. Kinetic Activity of Paracyclophane Bearing 1,4-Dihydronicotinamide and 2-Pyridinecarboxylic Acid Moieties as Effected by Zinc Ion

As regards the effect of zinc(II) ion on the reduction of hexachloroacetone, the kinetic activity of a paracyclophane (PCP) bearing 1,4-dihydronicotinamide (HNA) and 2-pyridinecarboxylic acid (Py) moieties, HNA-PCP-Py, has been investigated as an alcohol dehydrogenase model in reference to that of PCP-HNA in the light of their metal-coordination behavior.The reduction ability of PCP-HNA was significantly lowered as it underwent complex formation with zinc.On the other hand, HNA-PCP-Py showed an apparent rate maximum in a relatively lower concentration range of ZnCl2.The kinetic behavior was analyzed on the basis of the formation of two kinds of zinc complexes of HNA-PCP-Py: the 1:1 complex , in which both Py and HNA moieties are simultaneously coordinated to the same zinc ion, showed a decreased reactivity relative to metal-free HNA-PCP-Py; while the 2:1 complex (HNA-PCP-Py-ZnII-Py-PCP-HNA), in which HNA is free from metal-coordination, exercised a much enhanced activity, 7 times as reactive as metal-free HNA-PCP-Py.A plausible reaction mechanism for the enhanced reactivity has been discussed.

OXIDATION OF TERTIARY AMINES BY HEXACHLOROACETONE

Triethylamine and ethyldiisopropylamine are oxidized by hexachloroacetone.The vinyldialkylamines are acylated by hexachloroacetone, a discussion of the mechanism is presented.