619-28-3

Basic information

• Product Name: 3-Nitrophenyldichloromethane
• Synonyms: 1-(Dichloromethyl)-3-nitrobenzene;3-Nitrophenyldichloromethane;m-Nitrobenzal chloride;m-Nitrobenzylidene chloride;m-Nitrobenzylidene dichloride;α,α-Dichloro-m-nitrotoluene;ALPHA,ALPHA-DICHLORO-3-NITROTOLUENE
• CAS NO: 619-28-3
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.03
• Mol File: 619-28-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 283.7°C at 760 mmHg
• Flash Point: 125.4°C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 0.00532mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 3-Nitrophenyldichloromethane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitrophenyldichloromethane(619-28-3)
• EPA Substance Registry System: 3-Nitrophenyldichloromethane(619-28-3)

Safety Data

• Hazardous Substances Data: 619-28-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H5Cl2NO2/c8-7(9)5-2-1-3-6(4-5)10(11)12/h1-4,7H

Upstream product

• 98-87-3 benzylidene dichloride 
• 18483-95-9 2-<3-Nitro-benzyloxy>-tetrahydro-pyran 
• 62673-14-7 trimethyl(3-nitrobenzyloxy)silane 
• 3718-22-7 3-nitrobenzaldehyde hydrazone 
• 2243-80-3 3-nitrobenzophenone 
• 791-28-6 Triphenylphosphine oxide 
• 100-52-7 benzaldehyde 
• 86119-84-8 phosphoric acid 
• 290365-80-9 bis-(α-chloro-3-nitro-benzyl)-ether 
• 10025-87-3 trichlorophosphate 
• 10026-13-8 phosphorus pentachloride 
• 99-61-6 3-nitro-benzaldehyde 
• 7647-01-0 hydrogenchloride 
• 3431-62-7 3-nitrobenzaldoxime 

Downstream Products

• 62006-53-5 3,3'-dinitro-trans-stilbene 
• 99-61-6 3-nitro-benzaldehyde 
• 26029-52-7 m-benzotrifluoride 
• 29848-59-7 1-bromo-3-difluoromethyl-benzene 
• 368-99-0 3-difluoromethyl-phenylamine 
• 21911-67-1 N-(m-methylphenyl)glycine 
• 72949-61-2 1-(1-Methyl-1-nitro-ethyl)-4-(2-methyl-propenyl)-2-nitro-benzene 
• 72949-60-1 1-(1-Methyl-1-nitro-ethyl)-2-(2-methyl-propenyl)-4-nitro-benzene 
• 108-44-1 1-amino-3-methylbenzene 
• 403-25-8 1-(difluoromethyl)-3-nitrobenzene 
• 861349-20-4 1-ethoxy-4-ethoxymethyl-2-nitro-benzene 
• 59907-63-0 1-methoxy-2-methoxymethyl-4-nitro-benzene 
• 876494-02-9 1-methoxy-4-methoxymethyl-2-nitro-benzene 

Relevant articles and documents

One-pot, oxidative and selective conversion of benzylic silyl and tetrahydropyranyl ethers to gem-dichlorides using trichloroisocyanuric acid and triphenylphosphine as an efficient and neutral system

A one-pot and oxidative method is described for the first time for the conversion of benzylic trimethylsilyl (TMS) and tetrahydropyranyl (THP) ethers to gem-dichlorides using trichloroisocyanuric acid (TCCA) and triphenylphosphine (PPh3) in neutral media. Various theses substrates containing electron withdrawing or donating groups can be efficiently converted to their corresponding gem-dichlorides in good to excellent yields. The present method shows a high degree of chemoselectivity, and due to its one-pot nature is in accordance with green chemistry.

Synthesis of Aryldihalomethanes by Denitrogenative Dihalogenation of Benzaldehyde Hydrazones

We report a denitrogenative dihalogenation reaction of phenyldiazomethanes in which the hypervalent iodine reagents PhICl2 and TolIF2 act as surrogates for elemental chlorine and fluorine. Halogen transfer from iodane to aryldiazomethane is described, as is a tandem oxidative dihalogenation reaction between iodane and hydrazone. This is the first use of non-α-stabilized diazo compounds in this reaction, which provided an efficient synthesis of aryldifluoromethane (ArCHF2) and aryldichloromethane (ArCHCl2) derivatives. (Figure presented.).

One-pot, selective and mild conversion of benzylic alcohols to gem -dichlorides using chlorodiphenylphosphine and 2,3-dichloro-5,6-dicyanobenzoquinone as a new and neutral system

A mild and one-pot conversion of benzylic alcohols to their corresponding gem-dichlorides is reported for the first time using chlorodiphenylphosphine (ClPPh2) and 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in dichloromethane under neutral conditions and at room temperature. The present method can be efficiently used for preparation of gem-dichlorides even in the presence of some other functional groups with excellent chemoselectivity.