619-39-6

Basic information

• Product Name: 2-octyldecanoic acid
• Synonyms: 2-octyldecanoic acid;Dioctylacetic acid;2-octylcapric acid
• CAS NO: 619-39-6
• Molecular Formula: C₁₈H₃₆O₂
• Molecular Weight: 284.47724
• EINECS: 210-594-5
• Mol File: 619-39-6.mol
• Article Data: 15

Chemical Properties

• Melting Point: 38.5°C
• Boiling Point: 369.53°C (estimate)
• Flash Point: 225.6°C
• Appearance: /
• Density: 0.8833 (rough estimate)
• Vapor Pressure: 1.52E-07mmHg at 25°C
• Refractive Index: 1.4430 (estimate)
• CAS DataBase Reference: 2-octyldecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-octyldecanoic acid(619-39-6)
• EPA Substance Registry System: 2-octyldecanoic acid(619-39-6)

Safety Data

• Hazardous Substances Data: 619-39-6(Hazardous Substances Data)

Usage

General Description

2-octyldecanoic acid, also known as caprylic/capric triglyceride, is a chemical compound commonly used in skincare and cosmetic products. It is derived from coconut oil and glycerin, and is known for its emollient and skin-conditioning properties. 2-octyldecanoic acid is a natural alternative to mineral oil and is often used as a moisturizer, thickening agent, and emulsifier. It is also considered safe for use in personal care products and is often included in the formulation of lotions, creams, and serums due to its ability to improve skin texture and enhance the efficacy of other active ingredients.

InChI:InChI=1/C18H36O2/c1-3-5-7-9-11-13-15-17(18(19)20)16-14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H,19,20)

Upstream product

• 111-66-0 oct-1-ene 
• 2082-76-0 capric anhydride 
• 24251-93-2 2,2-dioctylmalonic acid diethyl ester 
• 1472-85-1 diethyl octylmalonate 
• 629-27-6 1-Iodooctane 
• 334-48-5 1-decanoic acid 
• 111-83-1 1-bromo-octane 
• 376395-26-5 2,2-dioctyl-acetoacetic acid ethyl ester 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 4372-37-6 2,2-dioctylmalonic acid 
• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 1223421-06-4 6,6'-bis-O-(2-octyldecanoyl)-2,3,4,2',3',4'-hexabenzyl-α,α'-trehalose 
• 45235-48-1 2-octyl-1-decanol 

Relevant articles and documents

BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS

The application relates to lipids of Formula (A), Formula (B) and Formula (1-1), and to lipid nanoparticles (empty or loaded LNPs) including such a lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Lipid nanoparticles further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS

The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY

The present application provides a composition comprising (1) a lipid composition comprising an ionizable amino lipid and a quaternary amine compound and (2) a polynucleotide. The present application also provides a composition comprising (1) a lipid composition comprising an asymmetric phospholipid, an ionizable amino lipid, and optionally a quaternary amine compound and (2) a polynucleotide, wherein the composition is formulated for intratumoral delivery of the polynucleotide. The present application further provides pharmaceutical compositions for intratumoral delivery comprising (1) a lipid composition comprising a compound of formula (I) and (2) therapeutic agent or a polynucleotide encoding the therapeutic agent, e.g., an mRNA encoding a therapeutic protein or a fragment thereof. Further provided is a method of increasing retention of a polynucleotide in a tumor tissue by using such a composition.