62009-37-4

Basic information

• Product Name: 5-Bromo-N,N-diethylpyridine-3-sulphonamide
• Synonyms: 5-Bromo-N,N-diethylpyridine-3-sulphonamide;5-Bromo-N,N-diethylpyridine-3-sulphonamide 95%;5-Bromo-N,N-diethylpyridine-3-sulfonamide;N,N-Diethyl 5-bromo-3-pyridinesulfonamide;5-bromo-N,N-diethyl-3-Pyridinesulfonamide;5-Bromo-N,N-diethylpyridine-3-sulphonamide95%
• CAS NO: 62009-37-4
• Molecular Formula: C₉H₁₃BrN₂O₂S
• Molecular Weight: 293.18072
• Product Categories: blocks;Bromides;Pyridines;Sulfonamides
• Mol File: 62009-37-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 376.5 °C at 760 mmHg
• Flash Point: 181.5 °C
• Appearance: /
• Density: 1.485 g/cm³
• Vapor Pressure: 7.22E-06mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Bromo-N,N-diethylpyridine-3-sulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-N,N-diethylpyridine-3-sulphonamide(62009-37-4)
• EPA Substance Registry System: 5-Bromo-N,N-diethylpyridine-3-sulphonamide(62009-37-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 62009-37-4(Hazardous Substances Data)

Usage

General Description

5-Bromo-N,N-diethylpyridine-3-sulphonamide is a chemical compound that is used in the field of medicine and pharmaceuticals. It is known for its sulfonamide group, which has antibacterial and anti-inflammatory properties. The bromo and diethyl groups contribute to its chemical structure and potential biological activity. This chemical is commonly used as a building block in the synthesis of other compounds with potential therapeutic applications, particularly in the development of new drugs for the treatment of various diseases and conditions. Its versatile structure and pharmacological properties make it an important compound in medicinal chemistry research and drug discovery efforts.

InChI:InChI=1/C9H13BrN2O2S/c1-3-12(4-2)15(13,14)9-5-8(10)6-11-7-9/h5-7H,3-4H2,1-2H3

Upstream product

• 16133-25-8 Pyridine-3-sulfonyl chloride 
• 109-89-7 diethylamine 
• 625-92-3 3,5-dibromopyridine 
• 65001-21-0 5-bromopyridine-3-sulphonyl chloride 

Relevant articles and documents

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl) pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease

Herein, we disclose the discovery of a series of 7-substituted triazolopyridines which culminated in the identification of 14 (CZC24758), a potent, orally bioavailable small-molecule inhibitor of PI3Kγ, an attractive drug target for inflammatory and autoimmune disorders. Compound 14 has excellent selectivity across the kinome, demonstrates good potency in cell based assays and furthermore exhibits in vivo efficacy in a collagen induced arthritis model in mouse after oral dosing.

Pyridine sulfonamides and their use as anticoccidial agents

Pyridine derivatives having the formula STR1 wherein R1 represents hydrogen atom, amino group or a group STR2 in which R5 and R6 may be the same or different and each represents an alkyl group of 1 to 4 carbon atoms or R5 is hydrogen atom and R6 represents an alkyl group of 1 to 4 carbon atoms, an alkenyl group of 3 or 4 carbon atoms or a benzyl group optionally substituted with halogen, cyano, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms; R2 represents nitro group, amino group or an alkylamino group of 1 to 3 carbon atoms; R3 and R4 individually represent hydrogen atom, an alkyl group of 1 to 4 carbon atoms, an alkoxyalkyl group which has 1 to 4 carbon atoms in the alkoxy moiety and 2 to 4 carbon atoms in the alkyl moiety, an alkenyl group of 3 or 4 carbon atoms, an alkanoyl group of 1 to 18 carbon atoms or a benzyl group optionally substituted with halogen, cyano, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms; provided that when R1 is hydrogen atom and R2 is nitro group, R3 and R4 may be the same or different and each represents said alkyl group or said alkoxyalkyl group or R3 is hydrogen atom and R4 is hydrogen atom, said alkyl group, said alkoxyalkyl group, said alkenyl group, said alkanoyl group or said benzyl group, when R1 is hydrogen atom and R2 is amino group or said alkylamino group, R3 and R4 individually is hydrogen atom or they may be the same or different and each represents said alkyl group, when R1 is amino group and R2 is nitro group, R3 and R4 may be the same or different and each represents said alkyl group or R 3 is hydrogen atom and R4 is said alkyl group or said alkenyl group, and when R1 is said group STR3 and R2 is nitro group, R3 and R4 are the same as defined above with respect to the R5 and R6. They are highly effective in the treatment of coccidiosis, especially that caused by the protozoa belonging to the species Eimeria tenella or E. necatrix.