6220-62-8

Basic information

• Product Name: 2'-deoxyguanosine 3'-(dihydrogen phosphate)
• Synonyms: 2'-deoxyguanosine 3'-(dihydrogen phosphate);EINECS 228-296-9;2'-deoxyguanosine 3'-phosphate;2'-Deoxy-3'-guanylic acid;2'-Deoxyguanosine-3'-phosphoric acid;3'-dGMP;Deoxy-ribo-guanilic acid;Desoxy-ribo-guanilic acid
• CAS NO: 6220-62-8
• Molecular Formula: C₁₀H₁₄N₅O₇P
• Molecular Weight: 347.221221
• EINECS: 228-296-9
• Mol File: 6220-62-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-deoxyguanosine 3'-(dihydrogen phosphate)(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-deoxyguanosine 3'-(dihydrogen phosphate)(6220-62-8)
• EPA Substance Registry System: 2'-deoxyguanosine 3'-(dihydrogen phosphate)(6220-62-8)

Safety Data

• Hazardous Substances Data: 6220-62-8(Hazardous Substances Data)

Usage

Definition

ChEBI: A deoxyguanosine phosphate having a monophosphate group located at the 3'-position.

Upstream product

• 72560-68-0 5'-O-acetyl-2'-deoxyguanosine 
• 89076-40-4 Phosphoric acid (2R,3S,5R)-5-(2-benzoylamino-6-hydroxy-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 2-cyano-ethyl ester 
• 69992-10-5 3',5'-di-O-acetyl-2'-deoxyguanosine 
• 961-07-9 2'-Deoxyguanosine 
• 112677-88-0 Phosphoric acid diallyl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester 
• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 
• 111050-58-9 Phosphoric acid mono-[(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl] ester 
• 51549-33-8 2’-deoxy-5’-O-tert-butyldimethylsilylguanosine 

Downstream Products

• 961-07-9 2'-Deoxyguanosine 
• 182230-62-2 N-(3'-monophosphate-2'-deoxyguanosin-8-yl)-4-methylaniline 
• 243663-85-6 Phosphoric acid mono-[(2R,3S,5R)-5-(2-amino-6-oxo-8-m-tolylamino-1,6-dihydro-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester 
• 176712-93-9 Phosphoric acid mono-{(2R,3S,5R)-5-[2-amino-8-(2,4-dimethyl-phenylamino)-6-oxo-1,6-dihydro-purin-9-yl]-2-hydroxymethyl-tetrahydro-furan-3-yl} ester 
• 16174-59-7 2’-deoxyguanosine-3’,5’-O-bisphosphate 
• 774539-74-1 C₃₀H₃₁N₆O₁₃P 

Relevant articles and documents

An efficient reagent for the phosphorylation of deoxyribonucleosides, DNA oligonucleotides, and their thermolytic analogues

(Chemical Equation Presented) The phosphoramidite 11 was prepared in three steps from methyl 2-mercaptoacetate and demonstrated efficiency in the synthesis of conventional 5′-/3′-phosphate/thiophosphate monoester derivatives of 2′-deoxyribonucleosides and DNA oligonucleotides. Moreover, the use of 11 has enabled the preparation of the dinucleoside phosphorothioate analogue 26 in high yields (>95%) with minimal cleavage (2%) of the thermolytic thiophosphate protecting group.

A facile method for the oxidation of nucleoside H-phosphonates to phosphates with bis(trimethylsilyl) peroxide

We have developed a convenient method for achieving the oxidation of nucleoside H-phosphonic acid monoesters and diesters with bis(trimethylsilyl) peroxide and N,O-bis(trimethylsilyl)acetamide in the presence of trimethylsilyl triflate as a catalyst.

Electrochemical removal of allylic protecting groups in nucleotide synthesis

Electrochemical, palladium(0)-mediated removal of allylic protecting groups of nucleosides and nucleotides is described. This method required no chromatographic treatment for isolation of the products.