623145-39-1Relevant articles and documents
Clickable peptide nucleic acids (cPNA) with tunable affinity
Chouikhi, Dalila,Barluenga, Sofia,Winssinger, Nicolas
supporting information; experimental part, p. 5476 - 5478 (2010/10/19)
Peptide nucleic acids (PNAs) are functional analogues of natural oligonucleotides. Herein, we report the synthesis of PNAs bearing a triazole in lieu of the amide bond assembled using a "click" cycloaddition, their hybridization properties as well as the DNA-templated coupling of the azide and alkyne PNA fragments. The Royal Society of Chemistry 2010.