62349-04-6

Basic information

• Product Name: ethyl 2-{[1-(3,6-dihydropyridin-1(2H)-yl)-1-hydroxyethyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• CAS NO: 62349-04-6
• Molecular Formula: C₁₈H₂₆N₂O₃S
• Molecular Weight: 350.4756
• Mol File: 62349-04-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 549.6°C at 760 mmHg
• Flash Point: 286.2°C
• Density: 1.269g/cm³
• Vapor Pressure: 6.49E-13mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: ethyl 2-{[1-(3,6-dihydropyridin-1(2H)-yl)-1-hydroxyethyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-{[1-(3,6-dihydropyridin-1(2H)-yl)-1-hydroxyethyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(62349-04-6)
• EPA Substance Registry System: ethyl 2-{[1-(3,6-dihydropyridin-1(2H)-yl)-1-hydroxyethyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(62349-04-6)

Safety Data

• Hazardous Substances Data: 62349-04-6(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 50618-83-2 2-(1-piperidinyl)acetyl chloride 
• 105-56-6 ethyl 2-cyanoacetate 
• 6802-76-2 ethyl 2-cyano-2-cyclohexylideneacetate 
• 110-89-4 piperidine 
• 60442-41-3 2-chloroacetylamino-3-carbethoxy-4,5,6,7-tetrahydrobenzothiophene 

Relevant articles and documents

Structure-activity relationships of 2-arylamido-5,7-dihydro-4H-thieno[2,3- c]pyran-3-carboxamide derivatives as cannabinoid receptor agonists and their analgesic action

SAR studies were performed on a series of 2-arylamido-5,7-dihydro-4H- thieno[2,3-c]pyran-3-carboxamide derivatives as cannabinoid receptor agonists. Starting from a HTS hit both potency and selectivity could be improved. Modifications to the thiophene fusion and C-3 amides were studied. A representative compound 3t produced analgesia when dosed orally in inflammatory pain models of writhing and carrageenan-induced allodynia.

ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES

Novel anthelmintic compositions containing thiophene derivatives as active ingredients are disclosed.

4,5,6,7,-tetrahydrobenzo (b) and 5,6,7,8,-tetrahydro 4H cyclohepta (b) thiophene

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